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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT6 All Species: 22.73
Human Site: S173 Identified Species: 38.46
UniProt: Q9ULM6 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULM6 NP_056270.2 557 63307 S173 T E Q P P P R S W I M L Q E P
Chimpanzee Pan troglodytes XP_518159 526 59880 N164 L F S V M C Y N V L C D K Y A
Rhesus Macaque Macaca mulatta XP_001092697 550 62412 P168 P E Q L P P R P W I T L K E R
Dog Lupus familis XP_538584 557 63238 S173 T E Q P P P R S W I M L Q E P
Cat Felis silvestris
Mouse Mus musculus Q8K3P5 557 63285 S173 T E Q P P P R S W I M L Q E P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505680 565 64018 S181 T E Q P P P R S W I M L Q E P
Chicken Gallus gallus XP_414612 563 64040 S179 T E Q P P P R S W I M L Q E P
Frog Xenopus laevis Q5BJ41 552 62758 S168 T E Q P P P R S W I M L Q E P
Zebra Danio Brachydanio rerio A2BHJ4 559 63359 P168 P E Q L P Q R P W I T L R E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732964 567 65029 P191 V N P P P Q R P W L P L A K P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502355 606 68585 N204 T H P P P E R N W V M I R H A
Sea Urchin Strong. purpuratus XP_779942 577 65769 P192 R T L P P A R P W I Q L S N P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W0Z9 602 66743 V232 I S I S G T D V T G H L D S N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9C2R2 793 88733 R379 V P L P P S P R K P I V V Q E
Conservation
Percent
Protein Identity: 100 94.2 78.6 98 N.A. 96.2 N.A. N.A. 93.6 93.7 95.1 74 N.A. 55.9 N.A. 45.2 55.1
Protein Similarity: 100 94.4 88.1 99.4 N.A. 97.8 N.A. N.A. 96.1 96.4 96.9 86.5 N.A. 70.9 N.A. 63.8 71.5
P-Site Identity: 100 0 60 100 N.A. 100 N.A. N.A. 100 100 100 53.3 N.A. 40 N.A. 40 46.6
P-Site Similarity: 100 20 66.6 100 N.A. 100 N.A. N.A. 100 100 100 60 N.A. 53.3 N.A. 66.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 26 N.A. 24.4
Protein Similarity: N.A. N.A. N.A. 43.1 N.A. 38.8
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 15 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 8 8 0 0 % D
% Glu: 0 58 0 0 0 8 0 0 0 0 0 0 0 58 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 8 0 0 8 0 % H
% Ile: 8 0 8 0 0 0 0 0 0 65 8 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 0 0 15 8 0 % K
% Leu: 8 0 15 15 0 0 0 0 0 15 0 79 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 50 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 15 0 0 0 0 0 8 8 % N
% Pro: 15 8 15 72 86 50 8 29 0 8 8 0 0 0 58 % P
% Gln: 0 0 58 0 0 15 0 0 0 0 8 0 43 8 0 % Q
% Arg: 8 0 0 0 0 0 79 8 0 0 0 0 15 0 15 % R
% Ser: 0 8 8 8 0 8 0 43 0 0 0 0 8 8 0 % S
% Thr: 50 8 0 0 0 8 0 0 8 0 15 0 0 0 0 % T
% Val: 15 0 0 8 0 0 0 8 8 8 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 79 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _