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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT6 All Species: 26.36
Human Site: S391 Identified Species: 44.62
UniProt: Q9ULM6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULM6 NP_056270.2 557 63307 S391 K N I I D K A S R N L K S S V
Chimpanzee Pan troglodytes XP_518159 526 59880 V377 E F G T I P L V L C A D L N S
Rhesus Macaque Macaca mulatta XP_001092697 550 62412 A384 V K N I L E K A S S R P G S P
Dog Lupus familis XP_538584 557 63238 S391 K N I I D K A S R N L Q S S V
Cat Felis silvestris
Mouse Mus musculus Q8K3P5 557 63285 S391 K N I I D K A S R S L K S S V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505680 565 64018 S399 K N I I D K A S R G L K S G S
Chicken Gallus gallus XP_414612 563 64040 S397 K N I I D K A S R S L K P G V
Frog Xenopus laevis Q5BJ41 552 62758 S386 K N I I D K A S R S L K S S V
Zebra Danio Brachydanio rerio A2BHJ4 559 63359 G384 S I A E R A S G S I N S S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732964 567 65029 S406 K T I I D E A S H S F R P G H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502355 606 68585 V419 S M M L T H E V S R V L E E V
Sea Urchin Strong. purpuratus XP_779942 577 65769 S408 K K I I E E E S V S F R P G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W0Z9 602 66743 A445 K G L E K I A A S A D I P M L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9C2R2 793 88733 D607 Q S V S V E S D I P K P E M P
Conservation
Percent
Protein Identity: 100 94.2 78.6 98 N.A. 96.2 N.A. N.A. 93.6 93.7 95.1 74 N.A. 55.9 N.A. 45.2 55.1
Protein Similarity: 100 94.4 88.1 99.4 N.A. 97.8 N.A. N.A. 96.1 96.4 96.9 86.5 N.A. 70.9 N.A. 63.8 71.5
P-Site Identity: 100 0 13.3 93.3 N.A. 93.3 N.A. N.A. 80 80 93.3 13.3 N.A. 40 N.A. 6.6 26.6
P-Site Similarity: 100 13.3 33.3 100 N.A. 100 N.A. N.A. 80 86.6 100 20 N.A. 60 N.A. 26.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. 26 N.A. 24.4
Protein Similarity: N.A. N.A. N.A. 43.1 N.A. 38.8
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 58 15 0 8 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 0 8 0 0 8 8 0 0 0 % D
% Glu: 8 0 0 15 8 29 15 0 0 0 0 0 15 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 15 0 0 0 0 % F
% Gly: 0 8 8 0 0 0 0 8 0 8 0 0 8 29 8 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 8 % H
% Ile: 0 8 58 65 8 8 0 0 8 8 0 8 0 0 0 % I
% Lys: 65 15 0 0 8 43 8 0 0 0 8 36 0 0 0 % K
% Leu: 0 0 8 8 8 0 8 0 8 0 43 8 8 0 8 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 0 0 15 0 % M
% Asn: 0 43 8 0 0 0 0 0 0 15 8 0 0 8 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 8 0 15 29 0 22 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 0 43 8 8 15 0 0 0 % R
% Ser: 15 8 0 8 0 0 15 58 29 43 0 8 43 43 15 % S
% Thr: 0 8 0 8 8 0 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 8 0 8 0 0 15 8 0 8 0 0 0 43 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _