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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNOT6
All Species:
33.94
Human Site:
Y246
Identified Species:
57.44
UniProt:
Q9ULM6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULM6
NP_056270.2
557
63307
Y246
Q
E
V
E
T
E
Q
Y
Y
S
F
F
L
V
E
Chimpanzee
Pan troglodytes
XP_518159
526
59880
R237
G
F
F
S
P
K
S
R
A
R
T
M
S
E
Q
Rhesus Macaque
Macaca mulatta
XP_001092697
550
62412
Y241
Q
E
V
E
T
E
Q
Y
F
T
L
F
L
P
A
Dog
Lupus familis
XP_538584
557
63238
Y246
Q
E
V
E
T
E
Q
Y
Y
S
F
F
L
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3P5
557
63285
Y246
Q
E
V
E
T
E
Q
Y
Y
S
F
F
L
V
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505680
565
64018
Y254
Q
E
V
E
T
E
Q
Y
Y
S
F
F
L
V
E
Chicken
Gallus gallus
XP_414612
563
64040
Y252
Q
E
V
E
T
E
Q
Y
Y
S
F
F
L
V
E
Frog
Xenopus laevis
Q5BJ41
552
62758
Y241
Q
E
V
E
T
E
Q
Y
Y
S
F
F
L
V
E
Zebra Danio
Brachydanio rerio
A2BHJ4
559
63359
Y241
Q
E
V
E
T
E
Q
Y
Y
T
F
F
L
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732964
567
65029
F264
Q
E
I
E
T
E
Q
F
Y
H
F
F
L
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502355
606
68585
F277
Q
E
V
E
T
E
Q
F
R
T
L
F
Q
P
E
Sea Urchin
Strong. purpuratus
XP_779942
577
65769
Y265
Q
E
V
E
T
E
Q
Y
Y
S
F
F
S
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W0Z9
602
66743
F305
Q
E
V
Q
N
D
H
F
E
E
F
F
L
P
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9C2R2
793
88733
F452
Q
E
I
A
T
D
V
F
R
D
F
F
S
P
E
Conservation
Percent
Protein Identity:
100
94.2
78.6
98
N.A.
96.2
N.A.
N.A.
93.6
93.7
95.1
74
N.A.
55.9
N.A.
45.2
55.1
Protein Similarity:
100
94.4
88.1
99.4
N.A.
97.8
N.A.
N.A.
96.1
96.4
96.9
86.5
N.A.
70.9
N.A.
63.8
71.5
P-Site Identity:
100
0
66.6
100
N.A.
100
N.A.
N.A.
100
100
100
80
N.A.
73.3
N.A.
60
80
P-Site Similarity:
100
13.3
80
100
N.A.
100
N.A.
N.A.
100
100
100
86.6
N.A.
86.6
N.A.
73.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
26
N.A.
24.4
Protein Similarity:
N.A.
N.A.
N.A.
43.1
N.A.
38.8
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
40
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
93
0
79
0
79
0
0
8
8
0
0
0
15
72
% E
% Phe:
0
8
8
0
0
0
0
29
8
0
79
93
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
15
0
72
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
43
0
% P
% Gln:
93
0
0
8
0
0
79
0
0
0
0
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
15
8
0
0
0
0
0
% R
% Ser:
0
0
0
8
0
0
8
0
0
50
0
0
22
0
0
% S
% Thr:
0
0
0
0
86
0
0
0
0
22
8
0
0
0
15
% T
% Val:
0
0
79
0
0
0
8
0
0
0
0
0
0
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
65
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _