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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDRG4 All Species: 9.09
Human Site: T254 Identified Species: 20
UniProt: Q9ULP0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.7
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULP0 NP_001123959.1 352 38459 T254 N S K L D P T T T T F L K M A
Chimpanzee Pan troglodytes A5A6K6 357 39342 E259 P H E D A V V E C N S K L D P
Rhesus Macaque Macaca mulatta XP_001101825 391 42925 D293 G D N A P A E D G V V E C N S
Dog Lupus familis XP_853829 504 54707 D406 G D N A P A E D G V V E C N S
Cat Felis silvestris
Mouse Mus musculus Q8BTG7 352 38490 T254 N S K L D P T T T T F L K M A
Rat Rattus norvegicus Q9Z2L9 352 38468 T254 N S K L D P T T T T F L K M A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507602 397 42989 N299 N S K L D P T N T T F L K M A
Chicken Gallus gallus XP_001231665 515 55908 E406 G D N A P A E E G V V E C N S
Frog Xenopus laevis Q6DJD3 367 40538 D269 G D N A P A E D S V V E C N S
Zebra Danio Brachydanio rerio Q5PR98 368 40449 E267 G D Q A P Y E E A A V E C N S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02485 325 35573 D225 G T K L E T V D A L L V T G S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.4 84.9 66.2 N.A. 97.7 96.8 N.A. 84.8 61.7 81.7 56.2 N.A. N.A. N.A. 26.4 N.A.
Protein Similarity: 100 75.6 85.4 67 N.A. 99.1 98.5 N.A. 86.6 64.4 89.3 73 N.A. N.A. N.A. 45.7 N.A.
P-Site Identity: 100 0 0 0 N.A. 100 100 N.A. 93.3 0 0 0 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 6.6 6.6 6.6 N.A. 100 100 N.A. 93.3 6.6 13.3 13.3 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 46 10 37 0 0 19 10 0 0 0 0 37 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 46 0 0 % C
% Asp: 0 46 0 10 37 0 0 37 0 0 0 0 0 10 0 % D
% Glu: 0 0 10 0 10 0 46 28 0 0 0 46 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % F
% Gly: 55 0 0 0 0 0 0 0 28 0 0 0 0 10 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 46 0 0 0 0 0 0 0 0 10 37 0 0 % K
% Leu: 0 0 0 46 0 0 0 0 0 10 10 37 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0 % M
% Asn: 37 0 37 0 0 0 0 10 0 10 0 0 0 46 0 % N
% Pro: 10 0 0 0 46 37 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 37 0 0 0 0 0 0 10 0 10 0 0 0 55 % S
% Thr: 0 10 0 0 0 10 37 28 37 37 0 0 10 0 0 % T
% Val: 0 0 0 0 0 10 19 0 0 37 46 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _