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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPCN1 All Species: 8.48
Human Site: S51 Identified Species: 18.67
UniProt: Q9ULQ1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULQ1 NP_001137291.1 816 94147 S51 I H D S Q A P S L S S G G E S
Chimpanzee Pan troglodytes XP_509396 816 94155 S51 I H D S Q A P S L S S G G E S
Rhesus Macaque Macaca mulatta XP_001111625 888 101692 S123 I H D S Q A P S L S S E G G S
Dog Lupus familis XP_534690 819 94589 L52 Q D S Q T S S L G L G G E S P
Cat Felis silvestris
Mouse Mus musculus Q9EQJ0 817 94478 L52 H N S Q V P S L V S G A D S P
Rat Rattus norvegicus Q9WTN5 817 94387 L52 P N S Q V P S L V S G A D S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519904 509 58353
Chicken Gallus gallus XP_415322 817 94827 L51 I I N D A S S L A A G D C C A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695923 805 92928 Q51 G A S D P R A Q N S L Q Q S W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001138446 882 101619 R51 T S P G F L S R Q T S S L S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94KI8 733 84855 L11 P L I G R D S L G G G G T D R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 90.8 93.1 N.A. 90.9 89.9 N.A. 45.2 82 N.A. 70.4 N.A. N.A. N.A. N.A. 43.5
Protein Similarity: 100 99.8 91.3 96.9 N.A. 94.7 94.6 N.A. 49.7 91.6 N.A. 82.9 N.A. N.A. N.A. N.A. 62.5
P-Site Identity: 100 100 86.6 6.6 N.A. 6.6 6.6 N.A. 0 6.6 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 86.6 13.3 N.A. 20 20 N.A. 0 33.3 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 28 10 0 10 10 0 19 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % C
% Asp: 0 10 28 19 0 10 0 0 0 0 0 10 19 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 10 19 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 19 0 0 0 0 19 10 46 37 28 10 0 % G
% His: 10 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 37 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 10 0 46 28 10 10 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 10 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 19 0 10 0 10 19 28 0 0 0 0 0 0 0 28 % P
% Gln: 10 0 0 28 28 0 0 10 10 0 0 10 10 0 0 % Q
% Arg: 0 0 0 0 10 10 0 10 0 0 0 0 0 0 10 % R
% Ser: 0 10 37 28 0 19 55 28 0 55 37 10 0 46 28 % S
% Thr: 10 0 0 0 10 0 0 0 0 10 0 0 10 0 0 % T
% Val: 0 0 0 0 19 0 0 0 19 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _