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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPCN1
All Species:
22.12
Human Site:
S745
Identified Species:
48.67
UniProt:
Q9ULQ1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULQ1
NP_001137291.1
816
94147
S745
T
R
L
L
E
T
L
S
Q
M
E
R
Y
Q
Q
Chimpanzee
Pan troglodytes
XP_509396
816
94155
S745
T
R
L
L
E
T
L
S
Q
M
E
R
Y
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001111625
888
101692
S817
T
R
L
L
E
T
L
S
Q
M
E
R
Y
Q
Q
Dog
Lupus familis
XP_534690
819
94589
S746
T
R
L
L
T
V
L
S
Q
M
E
K
H
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQJ0
817
94478
S746
T
R
L
L
D
T
L
S
Q
M
E
K
Y
Q
Q
Rat
Rattus norvegicus
Q9WTN5
817
94387
S746
T
R
L
L
D
T
L
S
Q
M
E
K
Y
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519904
509
58353
D439
H
E
A
L
A
L
L
D
E
A
G
Q
S
S
M
Chicken
Gallus gallus
XP_415322
817
94827
L744
S
Q
L
Q
K
I
V
L
Q
M
D
K
H
G
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695923
805
92928
Q735
V
T
N
L
T
S
L
Q
D
M
C
V
A
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138446
882
101619
L737
A
D
V
N
L
S
L
L
L
G
T
L
H
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KI8
733
84855
L663
Y
V
I
T
I
L
L
L
L
N
L
V
V
A
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
90.8
93.1
N.A.
90.9
89.9
N.A.
45.2
82
N.A.
70.4
N.A.
N.A.
N.A.
N.A.
43.5
Protein Similarity:
100
99.8
91.3
96.9
N.A.
94.7
94.6
N.A.
49.7
91.6
N.A.
82.9
N.A.
N.A.
N.A.
N.A.
62.5
P-Site Identity:
100
100
100
66.6
N.A.
86.6
86.6
N.A.
13.3
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
26.6
73.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
0
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
19
0
0
10
10
0
10
0
0
0
0
% D
% Glu:
0
10
0
0
28
0
0
0
10
0
55
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% H
% Ile:
0
0
10
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
37
0
0
0
% K
% Leu:
0
0
64
73
10
19
91
28
19
0
10
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
10
% M
% Asn:
0
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
10
0
0
0
10
64
0
0
10
0
46
64
% Q
% Arg:
0
55
0
0
0
0
0
0
0
0
0
28
0
10
0
% R
% Ser:
10
0
0
0
0
19
0
55
0
0
0
0
10
10
0
% S
% Thr:
55
10
0
10
19
46
0
0
0
0
10
0
0
0
0
% T
% Val:
10
10
10
0
0
10
10
0
0
0
0
19
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
46
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _