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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPCN1 All Species: 30.61
Human Site: S769 Identified Species: 67.33
UniProt: Q9ULQ1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULQ1 NP_001137291.1 816 94147 S769 S R T K S D L S L K M Y Q E E
Chimpanzee Pan troglodytes XP_509396 816 94155 S769 S R T K S D L S L K M Y Q E E
Rhesus Macaque Macaca mulatta XP_001111625 888 101692 S841 S R T K S D L S L K M Y Q E E
Dog Lupus familis XP_534690 819 94589 S770 S R T K S D L S L K M Y Q E E
Cat Felis silvestris
Mouse Mus musculus Q9EQJ0 817 94478 S770 S R T K S D L S L K M Y Q E E
Rat Rattus norvegicus Q9WTN5 817 94387 S770 S R T K S D L S L K M Y Q E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519904 509 58353 M463 K S D L S I K M Y Q E E I Q E
Chicken Gallus gallus XP_415322 817 94827 S768 S R T K S D L S M K M Y E E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695923 805 92928 K759 L G R R S R T K S D L S M K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001138446 882 101619 S761 Q R T K A D L S K T M Y A E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94KI8 733 84855 C687 D L E E E E K C Q G Q D S Q E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 90.8 93.1 N.A. 90.9 89.9 N.A. 45.2 82 N.A. 70.4 N.A. N.A. N.A. N.A. 43.5
Protein Similarity: 100 99.8 91.3 96.9 N.A. 94.7 94.6 N.A. 49.7 91.6 N.A. 82.9 N.A. N.A. N.A. N.A. 62.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 86.6 N.A. 6.6 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 100 N.A. 26.6 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 23.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 42.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 73 0 0 0 10 0 10 0 0 0 % D
% Glu: 0 0 10 10 10 10 0 0 0 0 10 10 10 73 91 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 10 0 0 73 0 0 19 10 10 64 0 0 0 10 0 % K
% Leu: 10 10 0 10 0 0 73 0 55 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 10 0 73 0 10 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 10 10 10 0 55 19 0 % Q
% Arg: 0 73 10 10 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 64 10 0 0 82 0 0 73 10 0 0 10 10 0 0 % S
% Thr: 0 0 73 0 0 0 10 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 73 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _