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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISY1
All Species:
9.09
Human Site:
S247
Identified Species:
15.38
UniProt:
Q9ULR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULR0
NP_065752.1
331
37567
S247
I
A
H
V
P
V
P
S
Q
Q
E
I
E
E
A
Chimpanzee
Pan troglodytes
XP_516736
431
48383
S347
I
A
H
V
P
V
P
S
Q
Q
E
I
E
E
A
Rhesus Macaque
Macaca mulatta
XP_001094091
362
41042
E280
R
L
A
R
G
E
K
E
E
E
E
E
E
E
E
Dog
Lupus familis
XP_849089
331
37489
S247
I
A
H
V
P
V
P
S
Q
Q
E
I
E
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZQ2
285
32971
E203
R
L
A
R
G
E
K
E
E
E
E
E
E
E
E
Rat
Rattus norvegicus
Q6AYB3
284
32843
E201
E
A
R
L
A
R
G
E
K
E
E
E
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414311
280
32383
E201
E
A
R
L
A
R
G
E
E
E
E
E
E
E
E
Frog
Xenopus laevis
NP_001085511
284
32391
N203
R
L
A
N
G
D
K
N
E
E
E
E
E
V
N
Zebra Danio
Brachydanio rerio
NP_001077032
285
32674
K188
V
M
A
E
A
V
E
K
W
K
A
D
K
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649768
272
31334
W189
I
Q
K
A
V
Q
E
W
R
E
K
M
A
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505803
267
31253
N188
E
K
N
I
E
R
I
N
K
E
F
A
E
K
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148910
311
36475
F233
E
A
A
R
E
V
L
F
E
G
V
E
E
E
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188509
300
35358
A222
S
V
G
A
A
A
A
A
A
R
E
V
L
F
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SHY8
239
27517
L161
P
L
E
T
R
D
D
L
R
K
Q
V
D
A
A
Conservation
Percent
Protein Identity:
100
76.3
78.1
96
N.A.
84.2
83.9
N.A.
N.A.
76.7
72.2
71.3
N.A.
49.5
N.A.
38
N.A.
Protein Similarity:
100
76.5
78.1
96.9
N.A.
85.1
84.8
N.A.
N.A.
80.9
79.4
77.9
N.A.
61
N.A.
55.2
N.A.
P-Site Identity:
100
100
20
100
N.A.
20
26.6
N.A.
N.A.
26.6
13.3
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
100
N.A.
33.3
46.6
N.A.
N.A.
46.6
33.3
40
N.A.
33.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
40.4
N.A.
40.4
N.A.
34.1
Protein Similarity:
N.A.
56.8
N.A.
57.4
N.A.
47.1
P-Site Identity:
N.A.
26.6
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
33.3
N.A.
26.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
36
15
29
8
8
8
8
0
8
8
8
8
36
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
15
8
0
0
0
0
8
8
0
8
% D
% Glu:
29
0
8
8
15
15
15
29
36
50
65
43
72
65
36
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% F
% Gly:
0
0
8
0
22
0
15
0
0
8
0
0
0
0
0
% G
% His:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
29
0
0
8
0
0
8
0
0
0
0
22
0
0
0
% I
% Lys:
0
8
8
0
0
0
22
8
15
15
8
0
8
8
0
% K
% Leu:
0
29
0
15
0
0
8
8
0
0
0
0
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
15
0
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
22
0
22
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
22
22
8
0
0
0
8
% Q
% Arg:
22
0
15
22
8
22
0
0
15
8
0
0
0
8
0
% R
% Ser:
8
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
22
8
36
0
0
0
0
8
15
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _