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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISY1
All Species:
8.18
Human Site:
S311
Identified Species:
13.85
UniProt:
Q9ULR0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULR0
NP_065752.1
331
37567
S311
T
A
V
P
M
G
P
S
L
P
T
T
S
P
R
Chimpanzee
Pan troglodytes
XP_516736
431
48383
S411
T
A
V
P
M
G
P
S
L
P
T
T
S
P
R
Rhesus Macaque
Macaca mulatta
XP_001094091
362
41042
K343
K
K
M
E
L
L
Q
K
Y
A
S
E
T
L
Q
Dog
Lupus familis
XP_849089
331
37489
S311
T
A
V
P
T
G
P
S
S
L
T
T
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZQ2
285
32971
K266
K
K
M
E
L
L
Q
K
Y
A
S
E
T
L
Q
Rat
Rattus norvegicus
Q6AYB3
284
32843
K265
K
K
M
E
L
L
Q
K
Y
A
S
E
T
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414311
280
32383
K261
K
K
M
E
L
L
Q
K
Y
A
S
E
T
L
M
Frog
Xenopus laevis
NP_001085511
284
32391
K265
K
K
M
E
L
L
Q
K
Y
A
S
E
T
L
L
Zebra Danio
Brachydanio rerio
NP_001077032
285
32674
R258
I
E
E
A
L
V
R
R
K
K
M
E
L
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649768
272
31334
D250
V
P
V
P
T
Q
Q
D
V
Q
E
A
L
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505803
267
31253
D248
V
L
L
P
T
Q
Q
D
I
E
E
M
L
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148910
311
36475
A292
K
E
L
L
S
K
Y
A
S
D
S
L
L
V
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188509
300
35358
A281
M
D
L
L
S
K
Y
A
S
E
D
L
V
E
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SHY8
239
27517
M220
P
E
W
E
L
P
T
M
D
E
V
A
Q
E
L
Conservation
Percent
Protein Identity:
100
76.3
78.1
96
N.A.
84.2
83.9
N.A.
N.A.
76.7
72.2
71.3
N.A.
49.5
N.A.
38
N.A.
Protein Similarity:
100
76.5
78.1
96.9
N.A.
85.1
84.8
N.A.
N.A.
80.9
79.4
77.9
N.A.
61
N.A.
55.2
N.A.
P-Site Identity:
100
100
0
80
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
80
N.A.
33.3
33.3
N.A.
N.A.
26.6
26.6
13.3
N.A.
26.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
40.4
N.A.
40.4
N.A.
34.1
Protein Similarity:
N.A.
56.8
N.A.
57.4
N.A.
47.1
P-Site Identity:
N.A.
0
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
20
N.A.
20
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
8
0
0
0
15
0
36
0
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
15
8
8
8
0
0
0
0
% D
% Glu:
0
22
8
43
0
0
0
0
0
22
15
43
0
15
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
43
36
0
0
0
15
0
36
8
8
0
0
0
0
0
% K
% Leu:
0
8
22
15
50
36
0
0
15
8
0
15
29
58
15
% L
% Met:
8
0
36
0
15
0
0
8
0
0
8
8
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
36
0
8
22
0
0
15
0
0
0
22
0
% P
% Gln:
0
0
0
0
0
15
50
0
0
8
0
0
8
0
36
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
29
% R
% Ser:
0
0
0
0
15
0
0
22
22
0
43
0
22
0
0
% S
% Thr:
22
0
0
0
22
0
8
0
0
0
22
22
36
0
0
% T
% Val:
15
0
29
0
0
8
0
0
8
0
8
0
8
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
0
36
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _