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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISY1
All Species:
15.15
Human Site:
Y122
Identified Species:
25.64
UniProt:
Q9ULR0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.46
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULR0
NP_065752.1
331
37567
Y122
P
G
N
R
G
Y
K
Y
F
G
A
A
K
D
L
Chimpanzee
Pan troglodytes
XP_516736
431
48383
Y222
P
G
N
R
G
Y
K
Y
F
G
A
A
K
D
L
Rhesus Macaque
Macaca mulatta
XP_001094091
362
41042
E165
L
R
E
K
G
H
W
E
V
R
I
K
E
L
G
Dog
Lupus familis
XP_849089
331
37489
Y122
P
G
N
R
G
Y
K
Y
F
G
A
A
K
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZQ2
285
32971
E88
L
R
E
K
G
H
W
E
V
R
I
K
E
L
G
Rat
Rattus norvegicus
Q6AYB3
284
32843
E88
L
R
E
K
G
H
W
E
V
R
I
K
E
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414311
280
32383
E88
L
R
E
K
G
H
W
E
V
R
I
R
E
L
G
Frog
Xenopus laevis
NP_001085511
284
32391
E88
I
R
E
K
G
H
W
E
V
R
I
K
E
L
G
Zebra Danio
Brachydanio rerio
NP_001077032
285
32674
E88
L
R
E
K
G
H
W
E
V
R
I
K
E
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649768
272
31334
N89
R
E
K
R
H
W
E
N
Q
I
S
S
L
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505803
267
31253
W88
L
I
K
L
K
H
A
W
E
Q
R
I
R
E
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148910
311
36475
Y131
G
R
G
P
G
Y
R
Y
F
G
A
A
R
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_188509
300
35358
Y129
G
R
G
P
G
Y
R
Y
F
G
A
A
K
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SHY8
239
27517
L69
S
R
I
Q
D
P
A
L
S
D
Y
Q
I
R
D
Conservation
Percent
Protein Identity:
100
76.3
78.1
96
N.A.
84.2
83.9
N.A.
N.A.
76.7
72.2
71.3
N.A.
49.5
N.A.
38
N.A.
Protein Similarity:
100
76.5
78.1
96.9
N.A.
85.1
84.8
N.A.
N.A.
80.9
79.4
77.9
N.A.
61
N.A.
55.2
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
6.6
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
26.6
26.6
N.A.
N.A.
26.6
26.6
26.6
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
40.4
N.A.
40.4
N.A.
34.1
Protein Similarity:
N.A.
56.8
N.A.
57.4
N.A.
47.1
P-Site Identity:
N.A.
53.3
N.A.
60
N.A.
0
P-Site Similarity:
N.A.
66.6
N.A.
66.6
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
0
36
36
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
0
22
8
% D
% Glu:
0
8
43
0
0
0
8
43
8
0
0
0
43
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
36
0
0
0
0
0
0
% F
% Gly:
15
22
15
0
79
0
0
0
0
36
0
0
0
8
50
% G
% His:
0
0
0
0
8
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
0
0
8
43
8
8
0
0
% I
% Lys:
0
0
15
43
8
0
22
0
0
0
0
36
29
15
0
% K
% Leu:
43
0
0
8
0
0
0
8
0
0
0
0
8
43
43
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
22
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
22
0
0
15
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
8
0
8
0
0
0
% Q
% Arg:
8
65
0
29
0
0
15
0
0
43
8
8
15
8
0
% R
% Ser:
8
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
43
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
43
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
36
0
36
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _