KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1H
All Species:
6.06
Human Site:
S139
Identified Species:
13.33
UniProt:
Q9ULR3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULR3
NP_065751.1
514
56448
S139
Q
L
K
E
N
S
E
S
E
G
V
S
C
H
Y
Chimpanzee
Pan troglodytes
XP_513628
505
54871
V139
G
R
R
S
V
T
G
V
P
R
E
P
S
R
G
Rhesus Macaque
Macaca mulatta
XP_001116776
514
56357
S139
Q
L
K
E
N
S
E
S
E
G
V
S
C
H
Y
Dog
Lupus familis
XP_531656
539
59447
E139
L
K
E
N
S
E
S
E
G
V
S
C
H
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
Q3UYC0
513
56362
E139
L
K
E
N
S
E
S
E
G
I
S
C
H
Y
W
Rat
Rattus norvegicus
Q5M821
513
56362
E139
L
K
E
N
S
E
S
E
G
I
S
C
H
Y
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507685
606
67811
F170
G
P
Q
P
S
L
G
F
Q
P
R
C
H
L
Q
Chicken
Gallus gallus
XP_418000
495
54949
R133
D
G
S
G
E
P
D
R
G
R
K
G
F
Y
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q05AL2
516
56543
Y139
V
K
E
L
D
F
H
Y
W
A
L
F
D
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502329
540
59857
S144
S
E
T
R
K
R
N
S
N
E
N
D
D
D
P
Sea Urchin
Strong. purpuratus
XP_798783
601
66691
I184
V
P
R
D
L
S
K
I
P
W
Y
S
G
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.8
98.8
84.4
N.A.
96.3
96.3
N.A.
44
59.7
N.A.
67.8
N.A.
N.A.
N.A.
36.1
38.1
Protein Similarity:
100
63.2
99.6
88.6
N.A.
99
98.8
N.A.
56.1
74.1
N.A.
83.3
N.A.
N.A.
N.A.
51.6
54
P-Site Identity:
100
0
100
0
N.A.
0
0
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
13.3
100
26.6
N.A.
26.6
26.6
N.A.
20
20
N.A.
26.6
N.A.
N.A.
N.A.
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
37
19
0
0
% C
% Asp:
10
0
0
10
10
0
10
0
0
0
0
10
19
10
0
% D
% Glu:
0
10
37
19
10
28
19
28
19
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
10
10
0
10
% F
% Gly:
19
10
0
10
0
0
19
0
37
19
0
10
10
10
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
37
19
10
% H
% Ile:
0
0
0
0
0
0
0
10
0
19
0
0
0
0
0
% I
% Lys:
0
37
19
0
10
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
28
19
0
10
10
10
0
0
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
28
19
0
10
0
10
0
10
0
0
0
0
% N
% Pro:
0
19
0
10
0
10
0
0
19
10
0
10
0
0
10
% P
% Gln:
19
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
10
19
10
0
10
0
10
0
19
10
0
0
10
0
% R
% Ser:
10
0
10
10
37
28
28
28
0
0
28
28
10
0
0
% S
% Thr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
19
0
0
0
10
0
0
10
0
10
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
28
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
10
0
0
46
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _