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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1H
All Species:
18.18
Human Site:
Y424
Identified Species:
40
UniProt:
Q9ULR3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULR3
NP_065751.1
514
56448
Y424
R
I
Y
D
L
S
K
Y
D
H
G
S
D
D
V
Chimpanzee
Pan troglodytes
XP_513628
505
54871
P419
L
T
Q
Y
E
H
C
P
D
D
V
L
V
L
G
Rhesus Macaque
Macaca mulatta
XP_001116776
514
56357
Y424
R
I
Y
D
L
S
K
Y
D
H
G
A
D
D
V
Dog
Lupus familis
XP_531656
539
59447
Y423
R
V
Y
D
L
S
K
Y
E
H
G
A
D
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UYC0
513
56362
Y423
R
V
Y
D
L
S
R
Y
E
H
G
A
D
D
V
Rat
Rattus norvegicus
Q5M821
513
56362
Y423
R
V
Y
D
L
S
K
Y
E
H
G
A
D
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507685
606
67811
W512
L
E
N
I
P
E
K
W
T
P
E
V
K
H
F
Chicken
Gallus gallus
XP_418000
495
54949
L413
E
H
C
P
D
D
V
L
V
L
G
T
D
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q05AL2
516
56543
F423
Q
V
Y
N
L
C
Q
F
E
H
G
A
D
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502329
540
59857
M431
S
V
T
N
L
R
D
M
N
T
L
T
D
K
D
Sea Urchin
Strong. purpuratus
XP_798783
601
66691
R494
K
V
Y
N
L
F
D
R
D
N
S
E
D
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.8
98.8
84.4
N.A.
96.3
96.3
N.A.
44
59.7
N.A.
67.8
N.A.
N.A.
N.A.
36.1
38.1
Protein Similarity:
100
63.2
99.6
88.6
N.A.
99
98.8
N.A.
56.1
74.1
N.A.
83.3
N.A.
N.A.
N.A.
51.6
54
P-Site Identity:
100
6.6
93.3
80
N.A.
73.3
80
N.A.
6.6
13.3
N.A.
46.6
N.A.
N.A.
N.A.
13.3
40
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
26.6
N.A.
93.3
N.A.
N.A.
N.A.
40
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
46
0
0
0
% A
% Cys:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
46
10
10
19
0
37
10
0
0
82
64
10
% D
% Glu:
10
10
0
0
10
10
0
0
37
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
64
0
0
10
10
% G
% His:
0
10
0
0
0
10
0
0
0
55
0
0
0
10
0
% H
% Ile:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
46
0
0
0
0
0
10
10
0
% K
% Leu:
19
0
0
0
73
0
0
10
0
10
10
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
28
0
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
46
0
0
0
0
10
10
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
46
0
0
0
0
10
10
0
0
0
% S
% Thr:
0
10
10
0
0
0
0
0
10
10
0
19
0
0
0
% T
% Val:
0
55
0
0
0
0
10
0
10
0
10
10
10
0
64
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
64
10
0
0
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _