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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1H
All Species:
20.91
Human Site:
Y467
Identified Species:
46
UniProt:
Q9ULR3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULR3
NP_065751.1
514
56448
Y467
D
P
D
D
P
H
R
Y
T
L
A
A
Q
D
L
Chimpanzee
Pan troglodytes
XP_513628
505
54871
A462
H
S
R
Y
T
A
L
A
Q
A
L
V
L
G
A
Rhesus Macaque
Macaca mulatta
XP_001116776
514
56357
Y467
D
P
D
D
P
H
R
Y
T
L
A
A
Q
D
L
Dog
Lupus familis
XP_531656
539
59447
F466
D
P
D
D
P
H
R
F
V
H
F
Y
D
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UYC0
513
56362
Y466
D
P
D
D
P
H
R
Y
T
L
A
A
Q
D
L
Rat
Rattus norvegicus
Q5M821
513
56362
Y466
D
P
D
D
P
H
R
Y
T
L
A
A
Q
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507685
606
67811
D555
K
Q
E
P
V
R
P
D
E
G
R
D
M
A
N
Chicken
Gallus gallus
XP_418000
495
54949
V456
T
V
V
A
Q
E
L
V
V
R
S
R
G
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q05AL2
516
56543
Y466
D
P
D
D
Q
H
R
Y
T
M
A
A
Q
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_502329
540
59857
R474
T
D
S
A
D
P
S
R
Y
T
Q
A
A
Q
D
Sea Urchin
Strong. purpuratus
XP_798783
601
66691
Y537
P
P
N
D
Y
K
K
Y
A
S
A
A
Q
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.8
98.8
84.4
N.A.
96.3
96.3
N.A.
44
59.7
N.A.
67.8
N.A.
N.A.
N.A.
36.1
38.1
Protein Similarity:
100
63.2
99.6
88.6
N.A.
99
98.8
N.A.
56.1
74.1
N.A.
83.3
N.A.
N.A.
N.A.
51.6
54
P-Site Identity:
100
0
100
46.6
N.A.
100
100
N.A.
0
6.6
N.A.
86.6
N.A.
N.A.
N.A.
6.6
46.6
P-Site Similarity:
100
0
100
53.3
N.A.
100
100
N.A.
6.6
13.3
N.A.
93.3
N.A.
N.A.
N.A.
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
10
0
10
10
10
55
64
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
10
55
64
10
0
0
10
0
0
0
10
10
46
10
% D
% Glu:
0
0
10
0
0
10
0
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% G
% His:
10
0
0
0
0
55
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
19
0
0
37
10
0
10
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
10
64
0
10
46
10
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
19
0
0
0
10
0
10
0
55
10
0
% Q
% Arg:
0
0
10
0
0
10
55
10
0
10
10
10
0
10
10
% R
% Ser:
0
10
10
0
0
0
10
0
0
10
10
0
0
0
0
% S
% Thr:
19
0
0
0
10
0
0
0
46
10
0
0
0
0
0
% T
% Val:
0
10
10
0
10
0
0
10
19
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
55
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _