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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCC3
All Species:
30.3
Human Site:
S388
Identified Species:
74.07
UniProt:
Q9ULS5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULS5
NP_065749.2
477
53768
S388
E
S
C
Q
T
R
I
S
K
L
E
L
H
Q
Q
Chimpanzee
Pan troglodytes
XP_001160901
484
53298
T392
E
S
C
L
T
R
V
T
K
L
E
L
Q
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001106781
383
43104
K314
Q
T
D
T
V
N
A
K
V
L
L
G
K
C
I
Dog
Lupus familis
XP_539724
634
71095
S545
E
S
C
Q
T
R
I
S
K
L
E
L
H
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R310
477
53703
S388
E
S
C
Q
T
R
I
S
K
L
E
L
H
Q
Q
Rat
Rattus norvegicus
NP_001101554
477
53560
S388
E
S
C
Q
T
R
I
S
K
L
E
L
H
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510126
446
49934
N375
A
L
Q
T
D
T
V
N
A
K
V
L
L
G
K
Chicken
Gallus gallus
XP_416147
471
53109
S382
E
S
C
Q
T
R
V
S
K
L
E
L
H
Q
Q
Frog
Xenopus laevis
NP_001084767
509
55651
S416
E
A
C
Q
T
R
I
S
K
M
E
L
Q
Q
Q
Zebra Danio
Brachydanio rerio
NP_001038278
476
53386
S387
E
V
C
Q
T
R
V
S
K
L
E
L
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.9
79.2
69.8
N.A.
93.9
94.9
N.A.
85.7
84.9
46.9
57.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
69
79.8
72.7
N.A.
96.8
97.6
N.A.
90.3
92.6
62.8
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
6.6
100
N.A.
100
100
N.A.
6.6
93.3
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
20
100
N.A.
100
100
N.A.
26.6
100
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
80
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
80
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
10
80
10
0
0
10
0
10
% K
% Leu:
0
10
0
10
0
0
0
0
0
80
10
90
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
70
0
0
0
0
0
0
0
0
30
80
80
% Q
% Arg:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
60
0
0
0
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
20
80
10
0
10
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
0
40
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _