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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC7A All Species: 34.55
Human Site: T449 Identified Species: 76
UniProt: Q9ULT0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULT0 NP_065191.2 858 96185 T449 K L R P S D P T V P L M A A K
Chimpanzee Pan troglodytes XP_515455 862 96398 T429 K L R P S D P T V P L M A A K
Rhesus Macaque Macaca mulatta XP_001113346 857 95745 T449 K L R P S D P T V P L M A A K
Dog Lupus familis XP_531812 812 91373 S415 A A K V C I G S L H W L E E A
Cat Felis silvestris
Mouse Mus musculus Q8BGB2 858 96138 T450 K L Q P S D P T V P L M A A K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506427 843 94241 T432 R L K P D D A T I P L L A A K
Chicken Gallus gallus NP_001026226 809 91043 T445 K L R P T D P T V P L L A A K
Frog Xenopus laevis NP_001090571 843 94707 T432 R L K P E D A T I P L L A A K
Zebra Danio Brachydanio rerio NP_001074072 844 94521 T433 R L K P D D P T I P L L A V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624273 818 92931 Q443 Q R E T S N S Q G M Q S R C H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784188 844 94184 T436 N V Q P D N V T V L L L A A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.7 96.7 88.2 N.A. 88.3 N.A. N.A. 50.3 67.7 50.7 50.2 N.A. N.A. 34.2 N.A. 38.5
Protein Similarity: 100 94.5 98.2 91.9 N.A. 94.5 N.A. N.A. 71.9 80.3 71.5 71.6 N.A. N.A. 55 N.A. 58.5
P-Site Identity: 100 100 100 0 N.A. 93.3 N.A. N.A. 60 86.6 60 60 N.A. N.A. 6.6 N.A. 46.6
P-Site Similarity: 100 100 100 26.6 N.A. 100 N.A. N.A. 86.6 100 86.6 86.6 N.A. N.A. 20 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 19 0 0 0 0 0 82 73 10 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 28 73 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 10 0 0 0 0 0 0 0 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 10 0 0 28 0 0 0 0 0 0 % I
% Lys: 46 0 37 0 0 0 0 0 0 0 0 0 0 0 82 % K
% Leu: 0 73 0 0 0 0 0 0 10 10 82 55 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 37 0 0 0 % M
% Asn: 10 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 82 0 0 55 0 0 73 0 0 0 0 0 % P
% Gln: 10 0 19 0 0 0 0 10 0 0 10 0 0 0 0 % Q
% Arg: 28 10 37 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 46 0 10 10 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 10 10 0 0 82 0 0 0 0 0 0 0 % T
% Val: 0 10 0 10 0 0 10 0 55 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _