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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECTD1
All Species:
24.24
Human Site:
S741
Identified Species:
48.48
UniProt:
Q9ULT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULT8
NP_056197.2
2612
289595
S741
Q
V
K
P
S
T
S
S
Q
P
I
L
S
A
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001114983
2611
289461
S741
Q
V
K
P
S
T
S
S
Q
P
I
L
S
A
P
Dog
Lupus familis
XP_850301
2078
231656
T327
S
L
G
S
E
F
V
T
G
W
T
G
K
R
G
Cat
Felis silvestris
Mouse
Mus musculus
NP_659037
2610
289211
S741
Q
V
K
P
S
T
S
S
Q
P
I
L
S
A
P
Rat
Rattus norvegicus
XP_343061
2610
289015
S741
Q
V
K
P
S
T
S
S
Q
P
I
L
S
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512305
2610
289238
S741
Q
V
K
P
S
T
S
S
Q
P
I
L
S
A
P
Chicken
Gallus gallus
XP_421227
2608
289019
A740
S
Q
V
K
P
S
T
A
S
Q
P
I
L
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002504
2576
285207
S741
Q
V
K
P
V
T
A
S
Q
P
I
L
S
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609369
2727
302131
S793
C
V
I
A
G
V
V
S
Q
P
I
L
P
T
A
Honey Bee
Apis mellifera
XP_001122009
2443
268430
R673
W
R
D
W
C
I
C
R
G
R
D
C
L
Y
V
Nematode Worm
Caenorhab. elegans
NP_501120
2761
304416
Q901
S
N
A
K
K
V
S
Q
K
L
E
V
P
A
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6WWW4
1888
202909
D137
A
A
A
A
R
S
A
D
E
D
D
D
N
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
78.4
N.A.
98
98.1
N.A.
96.7
94.3
N.A.
87.3
N.A.
48.2
53.2
38
N.A.
Protein Similarity:
100
N.A.
99.5
79
N.A.
98.9
99
N.A.
98.2
97
N.A.
92.8
N.A.
64
67.2
54.9
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
100
100
N.A.
100
0
N.A.
73.3
N.A.
40
0
13.3
N.A.
P-Site Similarity:
100
N.A.
100
13.3
N.A.
100
100
N.A.
100
33.3
N.A.
80
N.A.
40
0
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
17
0
0
17
9
0
0
0
0
0
50
17
% A
% Cys:
9
0
0
0
9
0
9
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
0
9
17
9
0
9
0
% D
% Glu:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
0
0
0
17
0
0
9
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
59
9
0
0
0
% I
% Lys:
0
0
50
17
9
0
0
0
9
0
0
0
9
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
9
0
59
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
50
9
0
0
0
0
59
9
0
17
0
42
% P
% Gln:
50
9
0
0
0
0
0
9
59
9
0
0
0
0
9
% Q
% Arg:
0
9
0
0
9
0
0
9
0
9
0
0
0
9
0
% R
% Ser:
25
0
0
9
42
17
50
59
9
0
0
0
50
9
9
% S
% Thr:
0
0
0
0
0
50
9
9
0
0
9
0
0
17
0
% T
% Val:
0
59
9
0
9
17
17
0
0
0
0
9
0
0
9
% V
% Trp:
9
0
0
9
0
0
0
0
0
9
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _