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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO5B All Species: 26.97
Human Site: S1643 Identified Species: 59.33
UniProt: Q9ULV0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULV0 NP_001073936 1849 213756 S1643 T G Y R K R S S S M A D G D N
Chimpanzee Pan troglodytes XP_001170365 1848 214427 S1644 T G L R K R T S S I A D E G T
Rhesus Macaque Macaca mulatta XP_001090434 1849 213576 S1644 T G Y R K R S S S M A D G D N
Dog Lupus familis XP_537345 1850 213656 S1645 T G Y R K R S S S M V D G D N
Cat Felis silvestris
Mouse Mus musculus P21271 1818 210552 S1613 T G Y R K R S S S M V D G E N
Rat Rattus norvegicus P70569 1846 213702 S1641 T G Y R K R S S S M V D G E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q02440 1829 212364 S1625 T G L R K R T S S I A D E G T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001155104 1839 212863 S1631 M G Y R N R S S S V D C E S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122188 1756 203360 I1559 D K P F Q I E I L Q D R Q S Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999655 1824 211646 T1617 G V R G S N S T I R E R E V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19524 1574 180662 K1401 C F N E L I M K R N F L S W K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.6 97.1 89.8 N.A. 88.7 89.8 N.A. N.A. 63 N.A. 72.1 N.A. N.A. 41.7 N.A. 50.3
Protein Similarity: 100 79.4 98 94.3 N.A. 94.1 95.1 N.A. N.A. 78.6 N.A. 83.9 N.A. N.A. 60 N.A. 68.9
P-Site Identity: 100 60 100 93.3 N.A. 86.6 86.6 N.A. N.A. 60 N.A. 46.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 73.3 100 93.3 N.A. 93.3 93.3 N.A. N.A. 73.3 N.A. 53.3 N.A. N.A. 6.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 19 64 0 28 0 % D
% Glu: 0 0 0 10 0 0 10 0 0 0 10 0 37 19 0 % E
% Phe: 0 10 0 10 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 73 0 10 0 0 0 0 0 0 0 0 46 19 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 19 0 10 10 19 0 0 0 0 0 % I
% Lys: 0 10 0 0 64 0 0 10 0 0 0 0 0 0 19 % K
% Leu: 0 0 19 0 10 0 0 0 10 0 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 10 0 0 46 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 10 0 0 0 10 0 0 0 0 46 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 10 0 0 10 0 0 % Q
% Arg: 0 0 10 73 0 73 0 0 10 10 0 19 0 0 0 % R
% Ser: 0 0 0 0 10 0 64 73 73 0 0 0 10 19 0 % S
% Thr: 64 0 0 0 0 0 19 10 0 0 0 0 0 0 19 % T
% Val: 0 10 0 0 0 0 0 0 0 10 28 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 55 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _