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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD4
All Species:
31.82
Human Site:
S472
Identified Species:
63.64
UniProt:
Q9ULV1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULV1
NP_036325.2
537
59881
S472
F
R
Y
S
A
D
D
S
N
M
A
V
E
M
L
Chimpanzee
Pan troglodytes
XP_001175326
537
59849
S472
F
R
Y
S
A
D
D
S
N
M
A
V
E
M
L
Rhesus Macaque
Macaca mulatta
XP_001103927
537
59890
S472
F
R
Y
S
A
D
D
S
N
M
A
V
E
M
L
Dog
Lupus familis
XP_848753
541
60627
S476
F
R
Y
S
A
D
D
S
N
M
A
V
E
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61088
537
60125
S472
F
R
Y
S
A
D
D
S
N
M
A
V
E
M
L
Rat
Rattus norvegicus
Q9QZH0
538
60336
S473
F
R
Y
S
A
D
D
S
N
M
A
V
E
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511743
486
54161
E426
D
E
A
G
V
A
V
E
T
L
K
M
F
M
S
Chicken
Gallus gallus
Q9IA05
525
58747
S460
F
R
Y
S
A
D
D
S
N
M
A
V
E
M
L
Frog
Xenopus laevis
Q9PT62
523
58722
S458
F
R
Y
T
A
D
D
S
N
M
A
V
E
M
L
Zebra Danio
Brachydanio rerio
XP_002664771
455
51006
M395
D
S
Y
M
A
A
E
M
L
R
I
F
M
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
D507
W
M
I
Q
W
H
R
D
I
C
K
P
F
S
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788346
818
91850
P468
W
M
D
G
E
A
T
P
N
I
E
V
F
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
97.9
N.A.
97
97.2
N.A.
83.4
93.3
89.3
70.7
N.A.
35.6
N.A.
N.A.
39.4
Protein Similarity:
100
100
100
98.1
N.A.
98.1
98.1
N.A.
87.5
95.3
93.3
76.1
N.A.
52.5
N.A.
N.A.
50.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
93.3
20
N.A.
0
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
26.6
N.A.
13.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
75
25
0
0
0
0
67
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
17
0
9
0
0
67
67
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
9
0
9
9
0
0
9
0
67
0
0
% E
% Phe:
67
0
0
0
0
0
0
0
0
0
0
9
25
0
0
% F
% Gly:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
9
9
9
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
84
% L
% Met:
0
17
0
9
0
0
0
9
0
67
0
9
9
84
0
% M
% Asn:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
0
0
0
0
9
0
0
9
0
0
0
0
0
% R
% Ser:
0
9
0
59
0
0
0
67
0
0
0
0
0
17
9
% S
% Thr:
0
0
0
9
0
0
9
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
9
0
0
0
0
75
0
0
0
% V
% Trp:
17
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _