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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSF4
All Species:
6.97
Human Site:
S281
Identified Species:
15.33
UniProt:
Q9ULV5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULV5
NP_001529.2
493
53110
S281
G
T
R
L
S
P
S
S
D
G
R
R
E
K
G
Chimpanzee
Pan troglodytes
XP_001161258
492
53052
S281
G
T
R
L
S
P
S
S
D
G
R
R
E
K
G
Rhesus Macaque
Macaca mulatta
XP_001108944
517
58258
V271
I
P
E
T
N
E
D
V
I
S
D
P
S
N
C
Dog
Lupus familis
XP_849103
517
56003
S281
P
G
G
S
V
D
E
S
S
P
V
V
R
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0L1
492
53237
G281
G
H
R
L
S
P
S
G
G
C
R
R
V
K
G
Rat
Rattus norvegicus
NP_001099647
399
43202
V226
D
T
G
F
L
P
P
V
L
A
G
A
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P38529
491
53580
S286
S
S
P
S
A
S
P
S
G
S
L
D
E
R
S
Frog
Xenopus laevis
P41154
451
49454
L270
S
P
S
P
C
P
S
L
E
A
S
P
S
P
V
Zebra Danio
Brachydanio rerio
NP_001013335
286
32683
H117
G
H
E
H
L
L
E
H
I
K
R
K
V
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22813
691
76915
S311
E
R
P
R
S
N
M
S
I
S
S
H
N
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQM7
485
54506
M275
I
V
K
Y
Q
P
P
M
H
E
Q
A
K
A
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
29.3
38.8
N.A.
86.7
63
N.A.
N.A.
34.7
38
32.5
N.A.
26.7
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
47.9
52.7
N.A.
90.2
67.4
N.A.
N.A.
48.9
53.4
43.5
N.A.
41.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
66.6
13.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
6.6
N.A.
66.6
13.3
N.A.
N.A.
33.3
20
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
19
0
19
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
10
% C
% Asp:
10
0
0
0
0
10
10
0
19
0
10
10
0
0
10
% D
% Glu:
10
0
19
0
0
10
19
0
10
10
0
0
28
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
10
19
0
0
0
0
10
19
19
10
0
0
0
28
% G
% His:
0
19
0
10
0
0
0
10
10
0
0
10
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
28
0
0
0
0
0
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
10
0
10
10
28
10
% K
% Leu:
0
0
0
28
19
10
0
10
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
0
10
10
0
% N
% Pro:
10
19
19
10
0
55
28
0
0
10
0
19
10
19
10
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
28
10
0
0
0
0
0
0
37
28
10
10
0
% R
% Ser:
19
10
10
19
37
10
37
46
10
28
19
0
19
10
10
% S
% Thr:
0
28
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
10
0
0
19
0
0
10
10
19
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _