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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPX2
All Species:
17.88
Human Site:
S292
Identified Species:
39.33
UniProt:
Q9ULW0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW0
NP_036244.2
747
85653
S292
S
E
L
R
K
H
P
S
S
P
A
R
V
T
K
Chimpanzee
Pan troglodytes
XP_001153533
746
85517
S291
S
E
L
R
K
H
P
S
S
P
A
R
V
T
K
Rhesus Macaque
Macaca mulatta
XP_001109645
746
85683
S291
S
E
L
R
K
H
P
S
S
P
A
R
V
T
K
Dog
Lupus familis
XP_850934
748
86144
A293
S
E
L
R
K
H
P
A
S
P
A
R
V
T
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_082385
745
85876
S294
S
E
L
R
K
H
S
S
T
P
A
R
G
T
R
Rat
Rattus norvegicus
NP_001101260
744
85432
S292
S
E
L
R
K
H
S
S
T
P
A
R
G
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516385
623
69684
P263
P
V
K
P
P
T
Q
P
V
A
F
D
L
E
I
Chicken
Gallus gallus
NP_989768
739
85048
P291
A
A
L
R
K
H
P
P
S
P
M
R
M
P
K
Frog
Xenopus laevis
NP_001086751
715
81991
H272
V
Q
V
T
K
G
G
H
T
V
P
K
P
F
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798362
948
108486
P492
K
I
S
P
A
K
V
P
H
G
P
T
V
P
K
Poplar Tree
Populus trichocarpa
XP_002327911
811
91572
S300
K
L
G
L
S
S
G
S
S
N
L
C
S
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.5
90.3
N.A.
79.2
79.1
N.A.
40.1
57.5
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
98.6
93.9
N.A.
87.6
87.4
N.A.
53
72.5
70
N.A.
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
0
60
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
6.6
73.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
0
10
0
10
55
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
55
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
0
10
0
0
10
19
0
0
10
0
0
19
0
0
% G
% His:
0
0
0
0
0
64
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
19
0
10
0
73
10
0
0
0
0
0
10
0
0
55
% K
% Leu:
0
10
64
10
0
0
0
0
0
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
10
0
0
19
10
0
46
28
0
64
19
0
10
19
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
64
0
0
0
0
0
0
0
64
0
0
19
% R
% Ser:
55
0
10
0
10
10
19
55
55
0
0
0
10
10
0
% S
% Thr:
0
0
0
10
0
10
0
0
28
0
0
10
0
55
0
% T
% Val:
10
10
10
0
0
0
10
0
10
10
0
0
46
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _