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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD10
All Species:
23.33
Human Site:
S176
Identified Species:
46.67
UniProt:
Q9ULW2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW2
NP_009128.1
581
65336
S176
F
R
P
Q
R
P
H
S
A
Q
E
H
P
L
K
Chimpanzee
Pan troglodytes
XP_522560
581
65327
S176
F
R
P
Q
R
P
H
S
A
Q
E
H
P
L
K
Rhesus Macaque
Macaca mulatta
XP_001109720
567
63652
S162
F
R
P
Q
R
P
H
S
A
Q
E
H
P
L
K
Dog
Lupus familis
XP_543357
581
65167
S176
F
R
P
Q
R
P
H
S
A
Q
E
H
P
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKG4
582
65300
S177
F
R
P
Q
R
P
H
S
A
Q
E
H
P
L
K
Rat
Rattus norvegicus
Q9QZH0
538
60336
P150
S
L
N
C
S
K
F
P
P
Q
N
D
H
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520614
537
59681
R145
P
G
D
G
G
P
G
R
P
G
C
R
G
P
A
Chicken
Gallus gallus
Q9PWH2
585
65927
T180
F
R
P
Q
R
P
S
T
G
H
D
L
Q
Q
H
Frog
Xenopus laevis
Q9DEB5
586
65560
S182
F
R
P
Q
R
P
S
S
G
H
E
I
Y
P
K
Zebra Danio
Brachydanio rerio
XP_002663237
580
64838
N177
S
R
P
P
R
P
G
N
S
Q
E
L
P
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
G193
T
T
R
K
H
Q
T
G
V
E
S
P
H
R
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790565
610
68431
G176
P
D
D
N
I
P
S
G
P
S
A
G
D
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.4
95
N.A.
92.7
50.5
N.A.
80
86.5
83.9
75.9
N.A.
39.2
N.A.
N.A.
48.5
Protein Similarity:
100
99.8
97.4
97.2
N.A.
96.2
66.6
N.A.
84.6
91.7
90.7
85.7
N.A.
57.4
N.A.
N.A.
63.9
P-Site Identity:
100
100
100
93.3
N.A.
100
6.6
N.A.
6.6
40
60
53.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
6.6
53.3
60
73.3
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
42
0
9
0
0
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
17
0
0
0
0
0
0
0
9
9
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
59
0
0
0
0
% E
% Phe:
59
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
9
0
17
17
17
9
0
9
9
9
0
% G
% His:
0
0
0
0
9
0
42
0
0
17
0
42
17
0
17
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
50
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
0
17
0
42
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
0
9
0
0
9
0
0
9
9
% N
% Pro:
17
0
67
9
0
84
0
9
25
0
0
9
50
17
0
% P
% Gln:
0
0
0
59
0
9
0
0
0
59
0
0
9
9
9
% Q
% Arg:
0
67
9
0
67
0
0
9
0
0
0
9
0
9
9
% R
% Ser:
17
0
0
0
9
0
25
50
9
9
9
0
0
0
0
% S
% Thr:
9
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _