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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD10
All Species:
30.91
Human Site:
S220
Identified Species:
61.82
UniProt:
Q9ULW2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW2
NP_009128.1
581
65336
S220
P
G
V
D
V
Y
W
S
R
E
D
K
R
F
A
Chimpanzee
Pan troglodytes
XP_522560
581
65327
S220
P
G
V
D
V
Y
W
S
R
E
D
K
R
F
A
Rhesus Macaque
Macaca mulatta
XP_001109720
567
63652
S206
P
G
V
D
V
Y
W
S
R
E
D
K
R
F
A
Dog
Lupus familis
XP_543357
581
65167
S220
P
G
V
D
V
Y
W
S
G
G
D
K
R
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKG4
582
65300
S221
P
G
V
D
V
Y
W
S
R
D
D
K
R
F
A
Rat
Rattus norvegicus
Q9QZH0
538
60336
V185
P
G
E
E
C
H
S
V
G
T
N
S
D
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520614
537
59681
G176
P
G
V
D
V
Y
W
G
R
D
D
K
R
F
A
Chicken
Gallus gallus
Q9PWH2
585
65927
S224
P
G
V
D
V
Y
W
S
K
D
D
K
Q
F
A
Frog
Xenopus laevis
Q9DEB5
586
65560
S225
S
S
V
D
V
Y
W
S
K
D
D
K
K
F
A
Zebra Danio
Brachydanio rerio
XP_002663237
580
64838
S220
S
N
V
D
V
Y
W
S
Q
G
D
K
R
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
D225
E
L
K
V
G
G
K
D
L
H
D
C
G
A
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790565
610
68431
S224
V
D
V
Y
F
Q
R
S
D
K
E
F
T
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.4
95
N.A.
92.7
50.5
N.A.
80
86.5
83.9
75.9
N.A.
39.2
N.A.
N.A.
48.5
Protein Similarity:
100
99.8
97.4
97.2
N.A.
96.2
66.6
N.A.
84.6
91.7
90.7
85.7
N.A.
57.4
N.A.
N.A.
63.9
P-Site Identity:
100
100
100
86.6
N.A.
93.3
13.3
N.A.
86.6
80
66.6
66.6
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
100
33.3
N.A.
93.3
100
86.6
80
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
67
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
9
0
75
0
0
0
9
9
34
84
0
9
0
0
% D
% Glu:
9
0
9
9
0
0
0
0
0
25
9
0
0
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
9
0
75
0
% F
% Gly:
0
67
0
0
9
9
0
9
17
17
0
0
9
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
9
0
17
9
0
75
9
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
9
0
0
9
0
0
0
9
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
42
0
0
0
59
0
0
% R
% Ser:
17
9
0
0
0
0
9
75
0
0
0
9
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% T
% Val:
9
0
84
9
75
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
75
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _