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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PYCARD All Species: 26.06
Human Site: S29 Identified Species: 71.67
UniProt: Q9ULZ3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULZ3 NP_037390.2 195 21627 S29 K F K L K L L S V P L R E G Y
Chimpanzee Pan troglodytes XP_001158687 195 21638 S29 K F K L K L L S V P L R E G Y
Rhesus Macaque Macaca mulatta XP_001112804 195 21540 S29 K F K L K L L S V P L R E G Y
Dog Lupus familis XP_848608 195 21781 S29 K F K M K L L S V P L R E G Y
Cat Felis silvestris
Mouse Mus musculus Q9EPB4 193 21440 T29 K F K M K L L T V Q L R E G Y
Rat Rattus norvegicus NP_758825 193 21635 T29 K F K M K L L T A P V R E G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507377 191 21323 S29 K F K T K L L S C P L R E G F
Chicken Gallus gallus
Frog Xenopus laevis NP_001086388 200 23168 D30 K F K G K L N D W E V N A G Y
Zebra Danio Brachydanio rerio Q9I9N6 203 22849 A41 E P R V T K S A I E K L K D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 91.7 76.9 N.A. 71.7 69.7 N.A. 58.4 N.A. 36.5 31 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 94.8 85.1 N.A. 81.5 80 N.A. 72.8 N.A. 56 52.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 80 73.3 N.A. 80 N.A. 46.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 N.A. 53.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 12 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 12 0 0 0 0 0 12 0 % D
% Glu: 12 0 0 0 0 0 0 0 0 23 0 0 78 0 12 % E
% Phe: 0 89 0 0 0 0 0 0 0 0 0 0 0 0 12 % F
% Gly: 0 0 0 12 0 0 0 0 0 0 0 0 0 89 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 89 0 89 0 89 12 0 0 0 0 12 0 12 0 0 % K
% Leu: 0 0 0 34 0 89 78 0 0 0 67 12 0 0 0 % L
% Met: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % N
% Pro: 0 12 0 0 0 0 0 0 0 67 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 0 0 0 78 0 0 0 % R
% Ser: 0 0 0 0 0 0 12 56 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 12 12 0 0 23 0 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 0 0 56 0 23 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _