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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMP17 All Species: 4.55
Human Site: S425 Identified Species: 11.11
UniProt: Q9ULZ9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULZ9 NP_057239.4 606 67006 S425 P R P V S D F S L P P G G I D
Chimpanzee Pan troglodytes XP_509485 604 66817 S425 P R P V S D F S L P P G G I D
Rhesus Macaque Macaca mulatta XP_001091146 562 62740 W391 L F S G P Q F W V F Q D R Q L
Dog Lupus familis XP_852332 661 73559 F490 Y P R P V S D F G L P P G G V
Cat Felis silvestris
Mouse Mus musculus Q9R0S3 578 64301 D407 K I V F F K G D R Y W V F K D
Rat Rattus norvegicus Q99PW6 618 70447 C443 S L G E L G S C L P R E G I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515193 574 63134 F402 Q N G K T Y L F R G T Q Y W R
Chicken Gallus gallus XP_415092 592 66478 I419 E E G Y P R P I S D F G L P P
Frog Xenopus laevis Q11005 477 54423 G306 G Y V W R L R G G K L Q N G Y
Zebra Danio Brachydanio rerio XP_698601 363 41642 R192 R S T I P P A R D A P D R C T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 46.4 73.6 N.A. 83.4 35.9 N.A. 44.4 74.1 32.5 47.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 58.8 78.2 N.A. 85.9 49.3 N.A. 56.8 81 45.6 52.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 13.3 N.A. 6.6 33.3 N.A. 0 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 13.3 N.A. 6.6 33.3 N.A. 6.6 6.6 0 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 20 10 10 10 10 0 20 0 0 40 % D
% Glu: 10 10 0 10 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 10 0 10 10 0 30 20 0 10 10 0 10 0 0 % F
% Gly: 10 0 30 10 0 10 10 10 20 10 0 30 40 20 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 10 0 0 0 10 0 0 0 0 0 30 0 % I
% Lys: 10 0 0 10 0 10 0 0 0 10 0 0 0 10 0 % K
% Leu: 10 10 0 0 10 10 10 0 30 10 10 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 20 10 20 10 30 10 10 0 0 30 40 10 0 10 10 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 10 20 0 10 0 % Q
% Arg: 10 20 10 0 10 10 10 10 20 0 10 0 20 0 10 % R
% Ser: 10 10 10 0 20 10 10 20 10 0 0 0 0 0 0 % S
% Thr: 0 0 10 0 10 0 0 0 0 0 10 0 0 0 10 % T
% Val: 0 0 20 20 10 0 0 0 10 0 0 10 0 0 10 % V
% Trp: 0 0 0 10 0 0 0 10 0 0 10 0 0 10 0 % W
% Tyr: 10 10 0 10 0 10 0 0 0 10 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _