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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO1
All Species:
9.09
Human Site:
S188
Identified Species:
25
UniProt:
Q9UM00
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM00
NP_061899.1
188
21175
S188
P
P
P
S
G
K
F
S
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_524948
239
27005
S239
P
P
P
S
G
K
F
S
_
_
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001086797
394
43631
S394
P
P
P
S
G
K
F
S
_
_
_
_
_
_
_
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507595
169
19251
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624879
183
21072
F182
F
G
P
P
P
Q
Q
F
K
_
_
_
_
_
_
Nematode Worm
Caenorhab. elegans
NP_495786
186
21281
L185
P
N
S
Q
M
N
Y
L
R
_
_
_
_
_
_
Sea Urchin
Strong. purpuratus
XP_001179268
183
20629
V182
F
G
Q
A
Q
P
G
V
K
_
_
_
_
_
_
Poplar Tree
Populus trichocarpa
XP_002322739
194
21207
N194
P
L
P
D
T
K
T
N
_
_
_
_
_
_
_
Maize
Zea mays
NP_001168552
199
21009
A185
A
P
P
R
A
V
A
A
A
G
G
G
L
F
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
85.1
N.A.
N.A.
N.A.
N.A.
N.A.
73.4
60.6
72.8
Protein Similarity:
100
78.6
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
87.7
N.A.
N.A.
N.A.
N.A.
N.A.
87.7
77.6
84.5
P-Site Identity:
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
11.1
11.1
0
P-Site Similarity:
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
22.2
11.1
Percent
Protein Identity:
43.8
42.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.9
62.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
37.5
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
50
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
12
12
0
12
12
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
23
0
0
0
0
0
34
12
0
0
0
0
0
12
0
% F
% Gly:
0
23
0
0
34
0
12
0
0
12
12
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
45
0
0
23
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
0
0
12
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
12
0
12
0
0
0
0
0
0
0
% N
% Pro:
56
45
67
12
12
12
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
12
12
12
12
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
0
0
12
34
0
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
45
78
78
78
78
78
78
% _