KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO1
All Species:
9.7
Human Site:
S60
Identified Species:
26.67
UniProt:
Q9UM00
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM00
NP_061899.1
188
21175
S60
K
K
E
T
I
T
E
S
A
G
R
Q
Q
K
K
Chimpanzee
Pan troglodytes
XP_524948
239
27005
S111
K
K
E
T
I
T
E
S
A
G
R
Q
Q
K
K
Rhesus Macaque
Macaca mulatta
XP_001086797
394
43631
S266
K
K
E
T
I
T
E
S
A
G
R
Q
Q
K
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507595
169
19251
E51
R
Q
Q
K
K
K
I
E
R
Q
E
E
K
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624879
183
21072
Q61
H
G
D
S
L
D
K
Q
Q
K
K
K
I
E
R
Nematode Worm
Caenorhab. elegans
NP_495786
186
21281
N61
V
G
D
T
N
D
K
N
I
K
R
K
L
E
R
Sea Urchin
Strong. purpuratus
XP_001179268
183
20629
N61
L
G
D
S
S
D
K
N
Q
K
K
K
L
E
R
Poplar Tree
Populus trichocarpa
XP_002322739
194
21207
I68
M
K
T
D
T
A
K
I
T
T
K
K
S
K
T
Maize
Zea mays
NP_001168552
199
21009
S65
M
K
S
G
S
N
S
S
G
A
A
S
S
S
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
85.1
N.A.
N.A.
N.A.
N.A.
N.A.
73.4
60.6
72.8
Protein Similarity:
100
78.6
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
87.7
N.A.
N.A.
N.A.
N.A.
N.A.
87.7
77.6
84.5
P-Site Identity:
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
53.3
53.3
Percent
Protein Identity:
43.8
42.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.9
62.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
34
12
12
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
12
0
34
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
34
0
0
0
34
12
0
0
12
12
0
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
34
0
12
0
0
0
0
12
34
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
34
0
12
12
12
0
0
0
12
0
0
% I
% Lys:
34
56
0
12
12
12
45
0
0
34
34
45
12
45
45
% K
% Leu:
12
0
0
0
12
0
0
0
0
0
0
0
23
12
0
% L
% Met:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
12
0
23
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
12
0
0
0
0
12
23
12
0
34
34
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
12
0
45
0
0
0
34
% R
% Ser:
0
0
12
23
23
0
12
45
0
0
0
12
23
12
0
% S
% Thr:
0
0
12
45
12
34
0
0
12
12
0
0
0
0
12
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _