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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO1
All Species:
10
Human Site:
T138
Identified Species:
27.5
UniProt:
Q9UM00
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM00
NP_061899.1
188
21175
T138
R
N
L
L
G
D
D
T
T
D
C
S
F
I
F
Chimpanzee
Pan troglodytes
XP_524948
239
27005
T189
R
N
L
L
G
D
D
T
T
D
C
S
F
I
F
Rhesus Macaque
Macaca mulatta
XP_001086797
394
43631
T344
R
N
L
L
G
D
D
T
T
D
C
S
F
I
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507595
169
19251
T120
N
L
L
G
E
D
Y
T
D
C
S
F
I
F
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624879
183
21072
G132
L
S
H
R
N
L
P
G
D
D
Y
T
E
C
S
Nematode Worm
Caenorhab. elegans
NP_495786
186
21281
M135
R
N
L
I
G
E
D
M
T
D
C
S
F
I
F
Sea Urchin
Strong. purpuratus
XP_001179268
183
20629
G132
I
S
H
R
N
L
L
G
N
D
F
T
D
S
S
Poplar Tree
Populus trichocarpa
XP_002322739
194
21207
G144
M
S
H
R
G
L
P
G
T
D
S
T
D
C
S
Maize
Zea mays
NP_001168552
199
21009
I135
A
K
L
P
F
A
P
I
P
L
V
Q
R
M
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.6
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
85.1
N.A.
N.A.
N.A.
N.A.
N.A.
73.4
60.6
72.8
Protein Similarity:
100
78.6
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
87.7
N.A.
N.A.
N.A.
N.A.
N.A.
87.7
77.6
84.5
P-Site Identity:
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
80
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
20
93.3
20
Percent
Protein Identity:
43.8
42.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
64.9
62.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
45
0
0
23
0
% C
% Asp:
0
0
0
0
0
45
45
0
23
78
0
0
23
0
0
% D
% Glu:
0
0
0
0
12
12
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
12
12
45
12
45
% F
% Gly:
0
0
0
12
56
0
0
34
0
0
0
0
0
0
0
% G
% His:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
12
0
0
0
0
12
45
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
12
67
34
0
34
12
0
0
12
0
0
0
0
12
% L
% Met:
12
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% M
% Asn:
12
45
0
0
23
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
34
0
12
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
45
0
0
34
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
0
34
0
0
0
0
0
0
0
0
23
45
0
12
45
% S
% Thr:
0
0
0
0
0
0
0
45
56
0
0
34
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _