Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZR1 All Species: 22.73
Human Site: T112 Identified Species: 38.46
UniProt: Q9UM11 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UM11 NP_001129669.1 496 55179 T112 E K V Q D P Q T E D R R L Q P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117911 714 76643 T333 E K V Q D P Q T E D R R L Q P
Dog Lupus familis XP_542177 493 54677 T112 E K V Q D P Q T E D R R L Q P
Cat Felis silvestris
Mouse Mus musculus Q9R1K5 493 54670 T112 E K V Q D P Q T E D R R L Q P
Rat Rattus norvegicus Q62623 499 54810 K109 E D G G T P T K K E H Q K A W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515034 292 32361
Chicken Gallus gallus NP_989485 495 55111 T112 E K V Q D P Q T E D R R L Q P
Frog Xenopus laevis NP_001080659 493 54681 T112 E K V Q D P Q T E D R R L Q P
Zebra Danio Brachydanio rerio NP_956547 495 54963 Q114 I E K V L D P Q T E D R R L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524852 478 53489 E101 D D V K T A G E E R N E N A Y
Honey Bee Apis mellifera XP_623291 486 54195 Q107 S I E D V K G Q C E E R R V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188191 1356 151017 N200 S S V D E F P N P S S Q I R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 E106 R A A M F G P E T P E K R D I
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 P134 D R I K N T R P S T R G N V H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 69 98.1 N.A. 97.7 37.6 N.A. 58.4 91.5 95.3 91.7 N.A. 68.7 69.7 N.A. 29.3
Protein Similarity: 100 N.A. 69 98.9 N.A. 98.9 54.9 N.A. 58.8 94.1 98.1 95.1 N.A. 78.8 80.6 N.A. 32
P-Site Identity: 100 N.A. 100 100 N.A. 100 13.3 N.A. 0 100 100 6.6 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 33.3 N.A. 0 100 100 20 N.A. 26.6 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 51.2 38.1 N.A.
Protein Similarity: N.A. N.A. N.A. 63.9 56.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 0 0 0 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 15 15 0 15 43 8 0 0 0 43 8 0 0 8 0 % D
% Glu: 50 8 8 0 8 0 0 15 50 22 15 8 0 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 8 15 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % H
% Ile: 8 8 8 0 0 0 0 0 0 0 0 0 8 0 8 % I
% Lys: 0 43 8 15 0 8 0 8 8 0 0 8 8 0 0 % K
% Leu: 0 0 0 0 8 0 0 0 0 0 0 0 43 8 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 8 0 0 8 0 15 0 0 % N
% Pro: 0 0 0 0 0 50 22 8 8 8 0 0 0 0 43 % P
% Gln: 0 0 0 43 0 0 43 15 0 0 0 15 0 43 15 % Q
% Arg: 8 8 0 0 0 0 8 0 0 8 50 58 22 8 0 % R
% Ser: 15 8 0 0 0 0 0 0 8 8 8 0 0 0 0 % S
% Thr: 0 0 0 0 15 8 8 43 15 8 0 0 0 0 0 % T
% Val: 0 0 58 8 8 0 0 0 0 0 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _