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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FZR1 All Species: 5.76
Human Site: Y420 Identified Species: 9.74
UniProt: Q9UM11 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UM11 NP_001129669.1 496 55179 Y420 E L V S T H G Y S Q N Q I L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117911 714 76643 H639 A N E L V S T H G Y S Q N Q I
Dog Lupus familis XP_542177 493 54677 H418 A N E L V S T H G Y S Q N Q I
Cat Felis silvestris
Mouse Mus musculus Q9R1K5 493 54670 H418 A N E L V S T H G Y S Q N Q I
Rat Rattus norvegicus Q62623 499 54810 F420 E L I S G H G F A Q N Q L V I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515034 292 32361 G217 Q H G L L A S G G G T A D R C
Chicken Gallus gallus NP_989485 495 55111 Y420 E L V S T H G Y S Q N Q I L V
Frog Xenopus laevis NP_001080659 493 54681 H418 A N E L V S T H G Y S Q N Q I
Zebra Danio Brachydanio rerio NP_956547 495 54963 H420 T N E L V S T H G Y S Q N Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524852 478 53489 H403 S S E L V S T H G Y S Q N Q I
Honey Bee Apis mellifera XP_623291 486 54195 H411 S S E L V S T H G Y S Q N Q I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188191 1356 151017 G1249 G L L A S G G G T A D R C I R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L3Z8 483 52822 S408 L V S T H G Y S Q N Q I I V W
Baker's Yeast Sacchar. cerevisiae P53197 566 62803 G448 G V L A T G G G T A D R R L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 69 98.1 N.A. 97.7 37.6 N.A. 58.4 91.5 95.3 91.7 N.A. 68.7 69.7 N.A. 29.3
Protein Similarity: 100 N.A. 69 98.9 N.A. 98.9 54.9 N.A. 58.8 94.1 98.1 95.1 N.A. 78.8 80.6 N.A. 32
P-Site Identity: 100 N.A. 6.6 6.6 N.A. 6.6 53.3 N.A. 0 100 6.6 6.6 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 N.A. 26.6 26.6 N.A. 26.6 93.3 N.A. 6.6 100 26.6 26.6 N.A. 26.6 26.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 51.2 38.1 N.A.
Protein Similarity: N.A. N.A. N.A. 63.9 56.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 15 0 8 0 0 8 15 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 15 0 8 0 0 % D
% Glu: 22 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 15 0 8 0 8 22 36 22 58 8 0 0 0 0 0 % G
% His: 0 8 0 0 8 22 0 50 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 8 22 8 58 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 8 29 15 58 8 0 0 0 0 0 0 0 8 22 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 36 0 0 0 0 0 0 0 8 22 0 50 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 22 8 72 0 50 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 15 8 8 8 % R
% Ser: 15 15 8 22 8 50 8 8 15 0 50 0 0 0 0 % S
% Thr: 8 0 0 8 22 0 50 0 15 0 8 0 0 0 0 % T
% Val: 0 15 15 0 50 0 0 0 0 0 0 0 0 15 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 8 15 0 50 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _