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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC10 All Species: 24.55
Human Site: S166 Identified Species: 38.57
UniProt: Q9UM13 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UM13 NP_055700.2 185 21252 S166 Y T P V E E S S I G K F P R C
Chimpanzee Pan troglodytes XP_001141102 114 12785 V96 Y T P S K I S V R V G N N F H
Rhesus Macaque Macaca mulatta XP_001094291 119 13489 N101 I S V R V G N N F H N L Q E I
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8K2H6 185 21248 S166 Y T P V E E S S I G K F P R C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514225 185 21175 S166 Y T P V E E S S I G K F P R C
Chicken Gallus gallus NP_001008467 185 21205 S166 Y T P V E E S S I G K F P R C
Frog Xenopus laevis NP_001089057 185 21176 S166 F T P V E E S S I G R F P R C
Zebra Danio Brachydanio rerio XP_001923028 185 21200 S166 Y T P V E E S S I G K Y P R C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V831 195 22282 H174 H A P V E G K H Y P L E L F G
Honey Bee Apis mellifera XP_396738 186 21258 L163 Y S P T Q D I L G P P A S Y I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783681 182 20449 T162 Y A P M Q N T T R N N R L P S
Poplar Tree Populus trichocarpa XP_002327795 192 21757 F173 Y G P R P N P F P H Q P F Q F
Maize Zea mays NP_001148648 201 22377 V182 Y G P R P N P V P H Q P F H F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPW2 192 21731 I173 Y G P R P N P I P H Q P F Q F
Baker's Yeast Sacchar. cerevisiae P53068 250 28758 H227 Y V P S N E P H Q D T H E W A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.6 62.1 N.A. N.A. 99.4 N.A. N.A. 97.8 97.8 94 90.8 N.A. 54.3 60.2 N.A. 64.3
Protein Similarity: 100 61.6 64.3 N.A. N.A. 99.4 N.A. N.A. 98.9 98.9 97.3 94.5 N.A. 73.3 75.8 N.A. 78.3
P-Site Identity: 100 26.6 0 N.A. N.A. 100 N.A. N.A. 100 100 86.6 93.3 N.A. 20 13.3 N.A. 13.3
P-Site Similarity: 100 33.3 20 N.A. N.A. 100 N.A. N.A. 100 100 100 100 N.A. 26.6 33.3 N.A. 40
Percent
Protein Identity: 52.6 49.7 N.A. 49.4 25.6 N.A.
Protein Similarity: 71.3 66.1 N.A. 70.8 42.8 N.A.
P-Site Identity: 13.3 13.3 N.A. 13.3 20 N.A.
P-Site Similarity: 26.6 20 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 0 0 0 0 0 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 40 % C
% Asp: 0 0 0 0 0 7 0 0 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 47 47 0 0 0 0 0 7 7 7 0 % E
% Phe: 7 0 0 0 0 0 0 7 7 0 0 34 20 14 20 % F
% Gly: 0 20 0 0 0 14 0 0 7 40 7 0 0 0 7 % G
% His: 7 0 0 0 0 0 0 14 0 27 0 7 0 7 7 % H
% Ile: 7 0 0 0 0 7 7 7 40 0 0 0 0 0 14 % I
% Lys: 0 0 0 0 7 0 7 0 0 0 34 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 7 0 0 7 7 14 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 27 7 7 0 7 14 7 7 0 0 % N
% Pro: 0 0 94 0 20 0 27 0 20 14 7 20 40 7 0 % P
% Gln: 0 0 0 0 14 0 0 0 7 0 20 0 7 14 0 % Q
% Arg: 0 0 0 27 0 0 0 0 14 0 7 7 0 40 0 % R
% Ser: 0 14 0 14 0 0 47 40 0 0 0 0 7 0 7 % S
% Thr: 0 47 0 7 0 0 7 7 0 0 7 0 0 0 0 % T
% Val: 0 7 7 47 7 0 0 14 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 80 0 0 0 0 0 0 0 7 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _