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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANAPC10 All Species: 13.64
Human Site: T76 Identified Species: 21.43
UniProt: Q9UM13 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UM13 NP_055700.2 185 21252 T76 R R K T T V K T L C I Y A D Y
Chimpanzee Pan troglodytes XP_001141102 114 12785 Q15 P P G A D P K Q L E R T G T V
Rhesus Macaque Macaca mulatta XP_001094291 119 13489 G20 P K Q L E R T G T V R E I G S
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8K2H6 185 21248 T76 R R K T T V K T L C I Y A D Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514225 185 21175 T76 R R K T T V K T L C I Y A D Y
Chicken Gallus gallus NP_001008467 185 21205 T76 R R K T T V K T L C I Y A D Y
Frog Xenopus laevis NP_001089057 185 21176 A76 R R K T T V K A L C V Y A D Y
Zebra Danio Brachydanio rerio XP_001923028 185 21200 M76 R R K T T V K M L C I Y A D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V831 195 22282 Q84 H K R T N I S Q I Y I Y T D Y
Honey Bee Apis mellifera XP_396738 186 21258 I76 T T I C D I C I Y T D Y K L D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783681 182 20449 L75 T T V H S V A L Y A D F K S D
Poplar Tree Populus trichocarpa XP_002327795 192 21757 L81 Q K K V K L Q L V V L Y V D F
Maize Zea mays NP_001148648 201 22377 L90 Q K K V Q L Q L V V L Y V D F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPW2 192 21731 L81 Q K K V K L Q L V V L Y V D F
Baker's Yeast Sacchar. cerevisiae P53068 250 28758 V135 S K R M D I C V M A I F F S M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.6 62.1 N.A. N.A. 99.4 N.A. N.A. 97.8 97.8 94 90.8 N.A. 54.3 60.2 N.A. 64.3
Protein Similarity: 100 61.6 64.3 N.A. N.A. 99.4 N.A. N.A. 98.9 98.9 97.3 94.5 N.A. 73.3 75.8 N.A. 78.3
P-Site Identity: 100 13.3 0 N.A. N.A. 100 N.A. N.A. 100 100 86.6 93.3 N.A. 33.3 6.6 N.A. 6.6
P-Site Similarity: 100 13.3 13.3 N.A. N.A. 100 N.A. N.A. 100 100 93.3 93.3 N.A. 60 13.3 N.A. 20
Percent
Protein Identity: 52.6 49.7 N.A. 49.4 25.6 N.A.
Protein Similarity: 71.3 66.1 N.A. 70.8 42.8 N.A.
P-Site Identity: 20 20 N.A. 20 6.6 N.A.
P-Site Similarity: 66.6 66.6 N.A. 66.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 7 7 0 14 0 0 40 0 0 % A
% Cys: 0 0 0 7 0 0 14 0 0 40 0 0 0 0 0 % C
% Asp: 0 0 0 0 20 0 0 0 0 0 14 0 0 67 14 % D
% Glu: 0 0 0 0 7 0 0 0 0 7 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 14 7 0 20 % F
% Gly: 0 0 7 0 0 0 0 7 0 0 0 0 7 7 0 % G
% His: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 20 0 7 7 0 47 0 7 0 0 % I
% Lys: 0 40 60 0 14 0 47 0 0 0 0 0 14 0 0 % K
% Leu: 0 0 0 7 0 20 0 27 47 0 20 0 0 7 0 % L
% Met: 0 0 0 7 0 0 0 7 7 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 14 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % P
% Gln: 20 0 7 0 7 0 20 14 0 0 0 0 0 0 0 % Q
% Arg: 40 40 14 0 0 7 0 0 0 0 14 0 0 0 0 % R
% Ser: 7 0 0 0 7 0 7 0 0 0 0 0 0 14 7 % S
% Thr: 14 14 0 47 40 0 7 27 7 7 0 7 7 7 0 % T
% Val: 0 0 7 20 0 47 0 7 20 27 7 0 20 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 14 7 0 74 0 0 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _