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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HPCAL4
All Species:
0
Human Site:
S177
Identified Species:
0
UniProt:
Q9UM19
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM19
NP_057341.1
191
22202
S177
E
F
K
E
A
A
K
S
D
P
S
I
V
L
L
Chimpanzee
Pan troglodytes
XP_001161893
498
54284
Rhesus Macaque
Macaca mulatta
XP_001113480
191
22090
Dog
Lupus familis
XP_849680
247
27836
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGZ1
191
22197
Rat
Rattus norvegicus
P35332
191
22227
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P42324
193
22251
Frog
Xenopus laevis
Q6DCM9
193
22267
Zebra Danio
Brachydanio rerio
Q6AXL4
192
21965
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42325
190
21875
Honey Bee
Apis mellifera
XP_392256
192
21952
Nematode Worm
Caenorhab. elegans
P36608
191
22003
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06389
190
21992
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
38.3
98.9
77.3
N.A.
99.4
98.9
N.A.
N.A.
66.8
66.8
64.5
N.A.
70.6
70.3
54.4
N.A.
Protein Similarity:
100
38.3
98.9
77.3
N.A.
99.4
98.9
N.A.
N.A.
82.3
82.3
83.3
N.A.
85.3
85.4
75.3
N.A.
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
0
0
0
N.A.
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
0
0
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
51.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
70.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
100
100
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% D
% Glu:
100
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
0
100
0
0
0
100
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _