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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHLA2
All Species:
1.21
Human Site:
S399
Identified Species:
5.33
UniProt:
Q9UM44
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM44
NP_009003.1
414
46850
S399
P
P
G
E
R
C
P
S
A
P
D
N
G
E
E
Chimpanzee
Pan troglodytes
XP_523213
534
57296
L517
G
E
G
S
K
T
A
L
Q
P
L
K
C
S
D
Rhesus Macaque
Macaca mulatta
XP_001094177
534
57283
L517
G
E
G
S
K
T
A
L
Q
P
L
K
H
S
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EV1
308
34001
K294
K
T
A
M
Q
P
L
K
V
T
S
P
G
E
D
Zebra Danio
Brachydanio rerio
XP_001338090
268
30054
F254
G
V
L
L
Y
F
Y
F
H
G
K
P
A
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202466
247
26818
S233
P
A
A
G
D
G
D
S
S
T
P
Q
N
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
21.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20.2
23.6
N.A.
N.A.
N.A.
N.A.
21
Protein Similarity:
100
38.2
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
39.6
35.2
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
100
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
34
0
0
0
34
0
17
0
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
17
0
0
0
0
0
0
17
0
0
% C
% Asp:
0
0
0
0
17
0
17
0
0
0
17
0
0
0
50
% D
% Glu:
0
34
0
17
0
0
0
0
0
0
0
0
0
34
17
% E
% Phe:
0
0
0
0
0
17
0
17
0
0
0
0
0
0
0
% F
% Gly:
50
0
50
17
0
17
0
0
0
17
0
0
34
0
0
% G
% His:
0
0
0
0
0
0
0
0
17
0
0
0
17
17
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
34
0
0
17
0
0
17
34
0
17
17
% K
% Leu:
0
0
17
17
0
0
17
34
0
0
34
0
0
0
0
% L
% Met:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
17
17
0
0
% N
% Pro:
34
17
0
0
0
17
17
0
0
50
17
34
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
34
0
0
17
0
0
0
% Q
% Arg:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
34
0
0
0
34
17
0
17
0
0
34
17
% S
% Thr:
0
17
0
0
0
34
0
0
0
34
0
0
0
0
0
% T
% Val:
0
17
0
0
0
0
0
0
17
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _