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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HHLA2
All Species:
0
Human Site:
Y274
Identified Species:
0
UniProt:
Q9UM44
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM44
NP_009003.1
414
46850
Y274
T
F
S
V
L
A
Y
Y
L
S
S
S
Q
N
T
Chimpanzee
Pan troglodytes
XP_523213
534
57296
R169
T
I
T
C
S
S
Y
R
G
Y
P
E
A
E
V
Rhesus Macaque
Macaca mulatta
XP_001094177
534
57283
R169
T
I
T
C
S
S
Y
R
G
Y
P
E
A
E
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EV1
308
34001
N175
W
Q
N
G
E
G
Q
N
M
T
E
N
I
T
T
Zebra Danio
Brachydanio rerio
XP_001338090
268
30054
E135
I
Y
A
A
P
Y
S
E
P
R
L
S
I
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202466
247
26818
L115
V
P
N
I
N
T
K
L
N
V
F
S
L
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
21.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20.2
23.6
N.A.
N.A.
N.A.
N.A.
21
Protein Similarity:
100
38.2
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
39.6
35.2
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
100
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
17
0
17
0
0
0
0
0
0
34
0
0
% A
% Cys:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
17
0
0
17
0
0
17
34
0
34
0
% E
% Phe:
0
17
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
0
17
0
17
0
0
34
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% H
% Ile:
17
34
0
17
0
0
0
0
0
0
0
0
34
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
17
0
0
17
17
0
17
0
17
0
17
% L
% Met:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
34
0
17
0
0
17
17
0
0
17
0
17
0
% N
% Pro:
0
17
0
0
17
0
0
0
17
0
34
0
0
0
17
% P
% Gln:
0
17
0
0
0
0
17
0
0
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
34
0
17
0
0
0
17
0
% R
% Ser:
0
0
17
0
34
34
17
0
0
17
17
50
0
0
0
% S
% Thr:
50
0
34
0
0
17
0
0
0
17
0
0
0
17
34
% T
% Val:
17
0
0
17
0
0
0
0
0
17
0
0
0
0
34
% V
% Trp:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
0
0
0
17
50
17
0
34
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _