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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO6
All Species:
39.09
Human Site:
Y749
Identified Species:
78.18
UniProt:
Q9UM54
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UM54
NP_004990.3
1294
149691
Y749
L
G
L
N
E
N
D
Y
K
F
G
L
T
K
V
Chimpanzee
Pan troglodytes
XP_001145254
1285
148711
Y749
L
G
L
N
E
N
D
Y
K
F
G
L
T
K
V
Rhesus Macaque
Macaca mulatta
NP_001098006
1253
144987
Y749
L
G
L
N
E
N
D
Y
K
F
G
L
T
K
V
Dog
Lupus familis
XP_853545
1284
148863
Y749
L
G
L
N
E
I
D
Y
K
F
G
L
T
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q64331
1265
146391
Y752
L
G
L
N
E
V
D
Y
K
F
G
L
T
Q
V
Rat
Rattus norvegicus
Q9QYF3
1828
211745
Y741
L
I
L
D
K
D
K
Y
Q
F
G
K
T
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506989
1284
148519
Y749
L
G
L
N
E
N
D
Y
K
F
G
L
T
K
V
Chicken
Gallus gallus
Q9I8D1
1276
147586
Y749
L
G
L
N
E
I
D
Y
K
F
G
L
T
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001004110
1267
146554
Y751
L
G
L
N
E
N
D
Y
K
F
G
L
T
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01989
1256
143696
F747
L
N
L
S
A
K
D
F
K
F
G
I
T
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91443
2098
239766
R747
I
V
I
Q
K
N
V
R
R
W
L
V
R
K
D
Sea Urchin
Strong. purpuratus
NP_999654
1267
145985
Y747
L
G
L
D
E
N
D
Y
Q
F
G
L
T
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.5
96.1
N.A.
89.3
21.5
N.A.
91.6
89.4
N.A.
81.9
N.A.
52.1
N.A.
21.4
56.9
Protein Similarity:
100
99
96.5
97.9
N.A.
92.5
38.7
N.A.
95.7
94.1
N.A.
90.8
N.A.
70.2
N.A.
35.3
73.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
46.6
N.A.
100
93.3
N.A.
93.3
N.A.
60
N.A.
13.3
86.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
80
N.A.
100
93.3
N.A.
100
N.A.
80
N.A.
53.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
9
84
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
92
0
0
0
0
0
% F
% Gly:
0
75
0
0
0
0
0
0
0
0
92
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
9
9
0
0
17
0
0
0
0
0
9
0
0
9
% I
% Lys:
0
0
0
0
17
9
9
0
75
0
0
9
0
84
0
% K
% Leu:
92
0
92
0
0
0
0
0
0
0
9
75
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
67
0
59
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
17
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
9
9
0
0
0
9
9
0
% R
% Ser:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
92
0
0
% T
% Val:
0
9
0
0
0
9
9
0
0
0
0
9
0
0
84
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _