KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
18.48
Human Site:
S205
Identified Species:
31.28
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
S205
L
V
K
P
E
E
L
S
K
Y
R
Q
V
A
S
Chimpanzee
Pan troglodytes
XP_508466
495
54079
P195
K
K
R
G
K
T
V
P
E
E
L
V
K
P
E
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
S596
L
V
K
P
E
E
L
S
K
Y
R
Q
V
A
S
Dog
Lupus familis
XP_853782
504
55132
S205
L
V
K
P
E
E
L
S
K
Y
R
Q
V
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
S205
L
V
K
P
E
E
L
S
K
Y
R
Q
V
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
Q206
V
E
A
R
G
A
Q
Q
V
P
G
R
S
P
R
Frog
Xenopus laevis
Q90ZL4
410
46744
T112
S
G
H
R
S
P
V
T
R
V
I
F
H
P
V
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
S206
L
V
R
A
E
D
L
S
K
Y
R
Q
V
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
R113
G
H
R
A
S
I
T
R
V
I
F
H
P
I
F
Honey Bee
Apis mellifera
XP_392284
504
55033
I204
D
L
L
P
Q
D
S
I
R
A
F
Q
T
L
A
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
L194
G
L
A
K
T
E
E
L
A
E
L
K
Q
T
A
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
P200
K
K
R
G
K
K
V
P
D
E
L
A
P
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
F209
S
V
D
A
L
E
K
F
T
Q
L
S
S
H
P
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
N201
T
F
P
Y
K
E
L
N
K
S
M
Y
Y
D
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
0
0
73.3
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
N.A.
13.3
20
86.6
N.A.
6.6
46.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
22
0
8
0
0
8
8
0
8
0
29
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
15
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
8
0
0
36
50
8
0
8
22
0
0
0
0
15
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
15
8
0
0
8
% F
% Gly:
15
8
0
15
8
0
0
0
0
0
8
0
0
8
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
8
8
8
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
8
8
0
0
8
0
% I
% Lys:
15
15
29
8
22
8
8
0
43
0
0
8
8
0
8
% K
% Leu:
36
15
8
0
8
0
43
8
0
0
29
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
36
0
8
0
15
0
8
0
0
15
22
8
% P
% Gln:
0
0
0
0
8
0
8
8
0
8
0
43
8
0
0
% Q
% Arg:
0
0
29
15
0
0
0
8
15
0
36
8
0
0
8
% R
% Ser:
15
0
0
0
15
0
8
36
0
8
0
8
15
8
36
% S
% Thr:
8
0
0
0
8
8
8
8
8
0
0
0
8
8
0
% T
% Val:
8
43
0
0
0
0
22
0
15
8
0
8
36
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
36
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _