KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
23.33
Human Site:
S281
Identified Species:
39.49
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
S281
P
S
Q
D
L
V
F
S
A
S
P
D
A
T
I
Chimpanzee
Pan troglodytes
XP_508466
495
54079
V271
T
K
K
V
T
S
V
V
F
H
P
S
Q
D
L
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
S672
P
S
Q
D
L
V
F
S
A
S
P
D
A
T
I
Dog
Lupus familis
XP_853782
504
55132
S281
P
S
Q
E
L
V
F
S
A
S
P
D
A
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
S281
P
S
Q
E
L
V
F
S
A
S
P
D
A
T
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
S282
P
S
Q
D
L
V
F
S
A
S
P
D
A
T
I
Frog
Xenopus laevis
Q90ZL4
410
46744
M188
G
F
E
C
L
R
T
M
H
G
H
D
H
N
V
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
S282
P
A
Q
A
V
V
F
S
A
S
S
D
S
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
M189
S
Y
E
C
I
K
T
M
H
G
H
D
H
N
V
Honey Bee
Apis mellifera
XP_392284
504
55033
M280
H
P
E
E
D
I
V
M
T
A
S
P
D
T
T
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
S270
N
I
T
A
I
S
A
S
A
D
S
H
I
R
V
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
I276
T
K
K
V
N
N
V
I
Y
H
P
T
E
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
D285
L
V
L
T
A
S
S
D
K
T
V
R
I
W
G
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
L277
D
S
K
T
N
K
V
L
R
E
I
E
V
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
N.A.
N.A.
N.A.
100
13.3
66.6
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
N.A.
N.A.
N.A.
100
26.6
86.6
N.A.
26.6
33.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
15
8
0
8
0
50
8
0
0
36
0
0
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
22
8
0
0
8
0
8
0
58
8
22
0
% D
% Glu:
0
0
22
22
0
0
0
0
0
8
0
8
8
0
0
% E
% Phe:
0
8
0
0
0
0
43
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
15
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
15
15
15
8
15
0
0
% H
% Ile:
0
8
0
0
15
8
0
8
0
0
8
0
15
0
43
% I
% Lys:
0
15
22
0
0
15
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
43
0
0
8
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
15
8
0
0
0
0
0
0
0
15
0
% N
% Pro:
43
8
0
0
0
0
0
0
0
0
50
8
0
0
0
% P
% Gln:
0
0
43
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
8
0
0
8
0
8
0
% R
% Ser:
8
43
0
0
0
22
8
50
0
43
22
8
8
0
8
% S
% Thr:
15
0
8
15
8
0
15
0
8
8
0
8
0
50
8
% T
% Val:
0
8
0
15
8
43
29
8
0
0
8
0
8
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _