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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
26.36
Human Site:
S323
Identified Species:
44.62
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
S323
A
T
G
D
Y
L
L
S
S
S
D
D
Q
Y
W
Chimpanzee
Pan troglodytes
XP_508466
495
54079
S313
E
S
A
V
T
G
L
S
L
H
A
T
G
D
Y
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
S714
A
T
G
D
Y
L
L
S
S
S
D
D
Q
Y
W
Dog
Lupus familis
XP_853782
504
55132
S323
A
T
G
D
Y
L
L
S
S
S
D
D
Q
Y
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
S323
A
T
G
D
Y
L
L
S
S
S
D
D
Q
Y
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
S324
A
T
G
D
Y
L
L
S
S
S
D
D
Q
Y
W
Frog
Xenopus laevis
Q90ZL4
410
46744
F230
T
G
Y
C
V
K
T
F
T
G
H
R
E
W
V
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
S324
A
T
G
D
Y
L
L
S
S
S
E
D
Q
Y
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
Y231
T
G
Y
C
V
K
T
Y
T
G
H
R
E
W
V
Honey Bee
Apis mellifera
XP_392284
504
55033
L322
H
P
T
G
D
Y
L
L
S
S
S
L
D
Q
H
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
S312
G
D
Y
I
L
S
A
S
D
D
S
Y
W
A
F
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
S318
D
A
A
V
T
G
L
S
L
H
A
T
G
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
A327
T
N
K
Y
F
V
S
A
S
L
D
S
T
W
C
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
D319
G
F
Q
S
Y
E
D
D
S
Q
Y
I
V
H
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
N.A.
100
0
93.3
N.A.
0
20
6.6
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
N.A.
100
20
100
N.A.
20
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
8
15
0
0
0
8
8
0
0
15
0
0
8
0
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
0
43
8
0
8
8
8
8
43
43
8
15
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
0
8
0
15
0
0
% E
% Phe:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
15
% F
% Gly:
15
15
43
8
0
15
0
0
0
15
0
0
15
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
15
15
0
0
8
8
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
15
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
43
65
8
15
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
0
43
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% R
% Ser:
0
8
0
8
0
8
8
65
65
50
15
8
0
0
8
% S
% Thr:
22
43
8
0
15
0
15
0
15
0
0
15
8
0
0
% T
% Val:
0
0
0
15
15
8
0
0
0
0
0
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
22
43
% W
% Tyr:
0
0
22
8
50
8
0
8
0
0
8
8
0
43
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _