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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
23.03
Human Site:
S397
Identified Species:
38.97
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
S397
G
H
S
G
P
I
T
S
I
A
F
S
E
N
G
Chimpanzee
Pan troglodytes
XP_508466
495
54079
N387
K
E
R
T
N
V
A
N
F
P
G
H
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
S788
G
H
S
G
P
I
T
S
I
A
F
S
E
N
G
Dog
Lupus familis
XP_853782
504
55132
S397
G
H
S
G
P
I
T
S
I
A
F
S
E
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
S397
G
H
S
G
P
I
T
S
I
A
F
S
E
N
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
S398
G
H
S
G
P
I
T
S
I
A
F
S
E
N
G
Frog
Xenopus laevis
Q90ZL4
410
46744
S304
T
G
S
E
T
K
R
S
G
K
P
G
P
F
L
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
A398
G
H
S
G
P
V
T
A
I
A
F
S
E
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
G305
A
G
A
D
N
K
K
G
H
H
Q
G
P
F
L
Honey Bee
Apis mellifera
XP_392284
504
55033
A396
G
H
S
G
P
I
T
A
I
S
F
S
E
N
G
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
I386
H
T
A
A
V
R
S
I
A
F
S
E
N
G
Y
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
N392
K
E
C
T
N
V
A
N
F
P
G
H
S
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
S401
G
H
N
G
E
I
T
S
I
S
F
S
E
N
G
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
C393
G
Y
W
M
V
V
E
C
D
Q
T
V
V
C
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
100
13.3
86.6
N.A.
0
86.6
0
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
N.A.
N.A.
N.A.
100
13.3
100
N.A.
6.6
100
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
8
0
0
15
15
8
43
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
15
0
8
8
0
8
0
0
0
0
8
58
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
15
8
58
0
0
15
8
% F
% Gly:
65
15
0
58
0
0
0
8
8
0
15
15
0
22
58
% G
% His:
8
58
0
0
0
0
0
0
8
8
0
15
0
0
0
% H
% Ile:
0
0
0
0
0
50
0
8
58
0
0
0
0
0
0
% I
% Lys:
15
0
0
0
0
15
8
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
22
0
0
15
0
0
0
0
8
58
0
% N
% Pro:
0
0
0
0
50
0
0
0
0
15
8
0
15
0
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
58
0
0
0
8
50
0
15
8
58
15
0
0
% S
% Thr:
8
8
0
15
8
0
58
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
15
29
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _