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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
19.7
Human Site:
T181
Identified Species:
33.33
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
T181
Q
K
L
Q
D
K
A
T
V
L
T
T
E
R
K
Chimpanzee
Pan troglodytes
XP_508466
495
54079
E171
E
L
V
G
M
T
P
E
I
I
Q
K
L
Q
D
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
T572
Q
K
L
Q
D
K
A
T
V
L
T
T
E
R
K
Dog
Lupus familis
XP_853782
504
55132
T181
Q
K
L
Q
D
K
A
T
V
L
T
T
E
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
T181
Q
K
L
Q
D
K
A
T
V
L
T
T
E
R
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
V182
K
P
Q
D
K
A
T
V
L
T
T
E
R
K
K
Frog
Xenopus laevis
Q90ZL4
410
46744
K88
S
G
G
P
I
G
Q
K
R
D
P
K
E
W
I
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
T182
Q
K
L
Q
D
K
A
T
V
L
T
T
E
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
R89
G
A
P
T
K
N
K
R
T
P
G
E
W
I
P
Honey Bee
Apis mellifera
XP_392284
504
55033
A180
I
Q
K
L
Q
E
R
A
T
V
L
T
Q
E
R
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
S170
L
A
K
L
E
E
K
S
K
S
L
T
A
E
R
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
D176
G
P
M
G
M
T
E
D
I
I
Q
K
L
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
A185
T
E
L
T
D
C
N
A
A
L
S
Q
Q
R
K
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
L177
K
A
P
K
W
P
I
L
K
N
L
E
L
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
13.3
6.6
100
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
33.3
100
100
N.A.
100
N.A.
N.A.
N.A.
33.3
6.6
100
N.A.
0
40
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
0
0
8
36
15
8
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
43
0
0
8
0
8
0
0
0
0
8
% D
% Glu:
8
8
0
0
8
15
8
8
0
0
0
22
43
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
8
8
15
0
8
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
8
0
15
15
0
0
0
8
8
% I
% Lys:
15
36
15
8
15
36
15
8
15
0
0
22
0
8
50
% K
% Leu:
8
8
43
15
0
0
0
8
8
43
22
0
22
8
0
% L
% Met:
0
0
8
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
15
15
8
0
8
8
0
0
8
8
0
0
0
8
% P
% Gln:
36
8
8
36
8
0
8
0
0
0
15
8
15
15
8
% Q
% Arg:
0
0
0
0
0
0
8
8
8
0
0
0
8
43
15
% R
% Ser:
8
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% S
% Thr:
8
0
0
15
0
15
8
36
15
8
43
50
0
0
0
% T
% Val:
0
0
8
0
0
0
0
8
36
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _