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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
22.42
Human Site:
T310
Identified Species:
37.95
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
T310
R
A
H
E
S
A
V
T
G
L
S
L
H
A
T
Chimpanzee
Pan troglodytes
XP_508466
495
54079
Q300
V
P
N
A
S
C
V
Q
V
V
R
A
H
E
S
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
T701
R
A
H
E
S
A
V
T
G
L
S
L
H
A
T
Dog
Lupus familis
XP_853782
504
55132
T310
R
A
H
E
S
A
V
T
G
L
S
L
H
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
T310
R
A
H
E
S
A
V
T
G
L
S
L
H
A
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
T311
R
A
H
E
G
S
V
T
G
L
S
L
H
A
T
Frog
Xenopus laevis
Q90ZL4
410
46744
K217
A
S
R
D
K
T
I
K
M
W
E
V
Q
T
G
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
T311
R
A
H
E
S
A
V
T
G
L
S
L
H
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
K218
A
S
R
D
R
T
I
K
M
W
E
V
A
T
G
Honey Bee
Apis mellifera
XP_392284
504
55033
V309
L
K
A
H
D
A
P
V
T
G
L
S
L
H
P
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
I299
H
Q
A
P
V
T
D
I
S
L
N
A
S
G
D
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
Q305
T
Q
N
G
S
C
S
Q
V
V
R
A
H
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
A314
D
H
S
A
E
V
R
A
V
T
V
H
A
T
N
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
D306
T
E
Y
F
I
W
A
D
N
R
G
T
I
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
20
100
100
N.A.
100
N.A.
N.A.
N.A.
86.6
0
100
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
40
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
26.6
100
N.A.
26.6
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
43
15
15
0
43
8
8
0
0
0
22
15
43
8
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
15
8
0
8
8
0
0
0
0
0
8
8
% D
% Glu:
0
8
0
43
8
0
0
0
0
0
15
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
8
0
0
0
43
8
8
0
0
15
15
% G
% His:
8
8
43
8
0
0
0
0
0
0
0
8
58
8
0
% H
% Ile:
0
0
0
0
8
0
15
8
0
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
8
0
0
15
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
50
8
43
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
8
0
8
0
0
0
8
% N
% Pro:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
0
15
0
0
0
0
0
15
0
0
0
0
8
0
0
% Q
% Arg:
43
0
15
0
8
0
8
0
0
8
15
0
0
0
0
% R
% Ser:
0
15
8
0
50
8
8
0
8
0
43
8
8
0
8
% S
% Thr:
15
0
0
0
0
22
0
43
8
8
0
8
0
22
43
% T
% Val:
8
0
0
0
8
8
50
8
22
15
8
15
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
15
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _