KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
22.73
Human Site:
T342
Identified Species:
38.46
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
T342
I
Q
T
G
R
V
L
T
K
V
T
D
E
T
S
Chimpanzee
Pan troglodytes
XP_508466
495
54079
F332
S
D
D
Q
Y
W
A
F
S
D
I
Q
T
G
R
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
T733
I
Q
T
G
R
V
L
T
K
V
T
D
E
T
S
Dog
Lupus familis
XP_853782
504
55132
T342
I
Q
T
G
R
V
L
T
K
V
T
D
E
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
T342
I
Q
T
G
R
V
L
T
K
V
T
D
E
T
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
T343
I
Q
T
G
R
V
L
T
K
V
T
D
E
S
S
Frog
Xenopus laevis
Q90ZL4
410
46744
I249
P
N
Q
D
G
T
L
I
A
S
C
S
N
D
Q
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
T343
I
Q
T
G
R
V
L
T
K
V
T
D
E
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
F250
V
H
I
E
G
S
I
F
A
T
C
S
N
D
Q
Honey Bee
Apis mellifera
XP_392284
504
55033
L341
D
I
R
T
G
R
L
L
T
K
V
A
G
Q
V
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
V331
S
G
K
S
L
C
K
V
S
V
E
P
G
S
Q
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
F337
S
E
D
R
H
W
A
F
S
D
I
T
T
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
Q346
S
S
G
L
C
L
A
Q
V
T
D
A
S
E
N
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
L338
V
E
Y
S
S
G
V
L
H
K
D
S
L
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
6.6
93.3
N.A.
0
6.6
6.6
0
P-Site Similarity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
100
6.6
100
N.A.
13.3
6.6
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
22
0
15
0
0
15
0
0
8
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
15
0
0
0
0
% C
% Asp:
8
8
15
8
0
0
0
0
0
15
15
43
0
15
0
% D
% Glu:
0
15
0
8
0
0
0
0
0
0
8
0
43
8
0
% E
% Phe:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
43
22
8
0
0
0
0
0
0
15
15
0
% G
% His:
0
8
0
0
8
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
43
8
8
0
0
0
8
8
0
0
15
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
43
15
0
0
0
0
0
% K
% Leu:
0
0
0
8
8
8
58
15
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
43
8
8
0
0
0
8
0
0
0
8
0
8
22
% Q
% Arg:
0
0
8
8
43
8
0
0
0
0
0
0
0
0
15
% R
% Ser:
29
8
0
15
8
8
0
0
22
8
0
22
8
15
36
% S
% Thr:
0
0
43
8
0
8
0
43
8
15
43
8
15
36
0
% T
% Val:
15
0
0
0
0
43
8
8
8
50
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _