Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPF19 All Species: 25.45
Human Site: Y320 Identified Species: 43.08
UniProt: Q9UMS4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMS4 NP_055317.1 504 55181 Y320 S L H A T G D Y L L S S S D D
Chimpanzee Pan troglodytes XP_508466 495 54079 T310 R A H E S A V T G L S L H A T
Rhesus Macaque Macaca mulatta XP_001084826 895 97815 Y711 S L H A T G D Y L L S S S D D
Dog Lupus familis XP_853782 504 55132 Y320 S L H A T G D Y L L S S S D D
Cat Felis silvestris
Mouse Mus musculus Q99KP6 504 55220 Y320 S L H A T G D Y L L S S S D D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMA2 505 55116 Y321 S L H A T G D Y L L S S S D D
Frog Xenopus laevis Q90ZL4 410 46744 V227 E V Q T G Y C V K T F T G H R
Zebra Danio Brachydanio rerio NP_958875 505 54715 Y321 S L H A T G D Y L L S S S E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KNS3 411 46441 V228 E V A T G Y C V K T Y T G H R
Honey Bee Apis mellifera XP_392284 504 55033 D319 L S L H P T G D Y L L S S S L
Nematode Worm Caenorhab. elegans Q10051 492 53189 L309 N A S G D Y I L S A S D D S Y
Sea Urchin Strong. purpuratus XP_001204257 498 53907 T315 R A H D A A V T G L S L H A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q94BR4 523 56848 F324 V H A T N K Y F V S A S L D S
Baker's Yeast Sacchar. cerevisiae P32523 503 56552 Y316 G T I G F Q S Y E D D S Q Y I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 56.3 99.4 N.A. 99.4 N.A. N.A. N.A. 94 22 85.3 N.A. 21.8 67.6 51.7 65.4
Protein Similarity: 100 95.4 56.3 99.8 N.A. 99.8 N.A. N.A. N.A. 96.6 39 94.6 N.A. 36.5 82.3 69.8 78.5
P-Site Identity: 100 20 100 100 N.A. 100 N.A. N.A. N.A. 100 0 93.3 N.A. 0 20 6.6 20
P-Site Similarity: 100 26.6 100 100 N.A. 100 N.A. N.A. N.A. 100 13.3 100 N.A. 13.3 20 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 42.4 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. 61.1 43.8 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 15 43 8 15 0 0 0 8 8 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 0 43 8 0 8 8 8 8 43 43 % D
% Glu: 15 0 0 8 0 0 0 0 8 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 8 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 8 0 0 15 15 43 8 0 15 0 0 0 15 0 0 % G
% His: 0 8 58 8 0 0 0 0 0 0 0 0 15 15 0 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 8 0 0 15 0 0 0 0 0 0 % K
% Leu: 8 43 8 0 0 0 0 8 43 65 8 15 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % R
% Ser: 43 8 8 0 8 0 8 0 8 8 65 65 50 15 8 % S
% Thr: 0 8 0 22 43 8 0 15 0 15 0 15 0 0 15 % T
% Val: 8 15 0 0 0 0 15 15 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 22 8 50 8 0 8 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _