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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
32.42
Human Site:
Y33
Identified Species:
54.87
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
Y33
E
R
R
L
I
E
K
Y
I
A
E
N
G
T
D
Chimpanzee
Pan troglodytes
XP_508466
495
54079
Y33
E
R
R
L
I
E
K
Y
I
A
E
N
G
T
D
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
Y424
E
R
R
L
I
E
K
Y
I
A
E
N
G
T
D
Dog
Lupus familis
XP_853782
504
55132
Y33
E
R
R
L
I
E
K
Y
I
A
E
N
G
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
Y33
E
R
R
L
I
E
K
Y
I
A
E
N
G
T
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
Y33
E
R
R
L
I
E
K
Y
I
A
E
N
G
T
D
Frog
Xenopus laevis
Q90ZL4
410
46744
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
Y33
E
R
R
L
I
E
K
Y
I
A
E
N
G
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
Honey Bee
Apis mellifera
XP_392284
504
55033
Y33
E
K
R
L
I
E
K
Y
L
A
E
N
G
V
D
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
K32
F
D
R
R
L
I
V
K
F
I
A
E
N
G
T
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
F33
E
K
R
L
I
E
K
F
I
S
E
N
G
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
Y35
I
Q
T
H
I
S
D
Y
G
K
C
P
V
T
G
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
K33
S
L
L
E
Q
Y
V
K
D
T
G
N
D
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
0
93.3
N.A.
0
80
6.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
0
93.3
N.A.
0
93.3
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
58
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
8
0
0
0
8
0
65
% D
% Glu:
65
0
0
8
0
65
0
0
0
0
65
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
8
0
65
8
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
72
8
0
0
58
8
0
0
0
0
8
% I
% Lys:
0
15
0
0
0
0
65
15
0
8
0
0
0
0
0
% K
% Leu:
0
8
8
65
8
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
72
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
50
72
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
8
0
0
0
50
8
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _