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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF19
All Species:
29.09
Human Site:
Y460
Identified Species:
49.23
UniProt:
Q9UMS4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMS4
NP_055317.1
504
55181
Y460
G
G
T
D
V
Q
I
Y
I
C
K
Q
W
T
E
Chimpanzee
Pan troglodytes
XP_508466
495
54079
L450
F
D
Q
S
G
T
Y
L
A
L
G
G
T
D
V
Rhesus Macaque
Macaca mulatta
XP_001084826
895
97815
Y851
G
G
T
D
V
Q
I
Y
I
C
K
Q
W
T
E
Dog
Lupus familis
XP_853782
504
55132
Y460
G
G
T
D
V
Q
I
Y
I
C
K
Q
W
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP6
504
55220
Y460
G
G
T
D
V
Q
I
Y
I
C
K
Q
W
T
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMA2
505
55116
Y461
G
G
T
D
V
Q
I
Y
I
C
K
Q
W
T
E
Frog
Xenopus laevis
Q90ZL4
410
46744
Y367
K
T
I
R
I
W
D
Y
K
N
K
R
C
M
K
Zebra Danio
Brachydanio rerio
NP_958875
505
54715
Y461
G
G
S
D
I
R
V
Y
I
C
K
Q
W
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
L368
K
T
I
R
V
W
D
L
R
N
K
R
C
M
K
Honey Bee
Apis mellifera
XP_392284
504
55033
Y459
A
G
T
D
V
R
V
Y
L
C
K
Q
W
Q
E
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
H449
G
Q
K
V
Q
V
L
H
V
K
S
W
S
E
V
Sea Urchin
Strong. purpuratus
XP_001204257
498
53907
P455
C
L
G
Y
T
E
A
P
S
S
T
R
H
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94BR4
523
56848
S464
I
R
V
F
Q
A
A
S
V
K
A
E
W
N
P
Baker's Yeast
Sacchar. cerevisiae
P32523
503
56552
N456
K
F
D
K
K
T
K
N
W
T
K
D
E
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
56.3
99.4
N.A.
99.4
N.A.
N.A.
N.A.
94
22
85.3
N.A.
21.8
67.6
51.7
65.4
Protein Similarity:
100
95.4
56.3
99.8
N.A.
99.8
N.A.
N.A.
N.A.
96.6
39
94.6
N.A.
36.5
82.3
69.8
78.5
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
100
13.3
66.6
N.A.
13.3
66.6
6.6
0
P-Site Similarity:
100
0
100
100
N.A.
100
N.A.
N.A.
N.A.
100
33.3
100
N.A.
26.6
86.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.4
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.1
43.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
15
0
8
0
8
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
50
0
0
15
0
0
% C
% Asp:
0
8
8
50
0
0
15
0
0
0
0
8
0
8
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
8
8
15
50
% E
% Phe:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
50
8
0
8
0
0
0
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
8
0
15
0
15
0
36
0
43
0
0
0
0
0
8
% I
% Lys:
22
0
8
8
8
0
8
0
8
15
72
0
0
0
15
% K
% Leu:
0
8
0
0
0
0
8
15
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
15
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% P
% Gln:
0
8
8
0
15
36
0
0
0
0
0
50
0
8
0
% Q
% Arg:
0
8
0
15
0
15
0
0
8
0
0
22
0
0
0
% R
% Ser:
0
0
8
8
0
0
0
8
8
8
8
0
8
8
8
% S
% Thr:
0
15
43
0
8
15
0
0
0
8
8
0
8
36
0
% T
% Val:
0
0
8
8
50
8
15
0
15
0
0
0
0
8
15
% V
% Trp:
0
0
0
0
0
15
0
0
8
0
0
8
58
0
0
% W
% Tyr:
0
0
0
8
0
0
8
58
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _