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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SUFU
All Species:
34.55
Human Site:
S349
Identified Species:
63.33
UniProt:
Q9UMX1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UMX1
NP_057253.2
484
53947
S349
S
R
K
D
S
L
E
S
D
S
S
T
A
I
I
Chimpanzee
Pan troglodytes
XP_001171586
481
53011
S349
S
R
K
D
S
L
E
S
D
S
S
T
A
I
I
Rhesus Macaque
Macaca mulatta
XP_001112934
526
58552
S349
S
R
K
D
S
L
E
S
D
S
S
T
A
I
I
Dog
Lupus familis
XP_851176
484
53891
S349
S
R
K
D
S
L
E
S
D
S
S
T
A
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0P7
484
53938
S349
S
R
K
D
S
L
G
S
D
S
S
T
A
I
I
Rat
Rattus norvegicus
NP_001020070
485
54062
S350
S
R
K
D
S
L
G
S
D
I
S
T
A
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511575
391
43818
A261
S
L
E
S
E
S
S
A
A
I
I
P
H
E
L
Chicken
Gallus gallus
NP_989595
484
53730
S349
S
R
K
D
S
L
E
S
E
S
S
A
A
I
I
Frog
Xenopus laevis
NP_001086013
474
53272
S339
S
R
K
D
S
L
E
S
E
S
S
A
A
I
I
Zebra Danio
Brachydanio rerio
NP_958466
485
54269
S350
S
R
K
D
S
L
E
S
E
S
S
A
A
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_536750
468
52769
P338
L
D
F
Q
A
Q
A
P
N
C
I
S
L
D
G
Honey Bee
Apis mellifera
XP_393834
431
48050
E301
I
K
P
I
I
K
S
E
R
L
S
P
C
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796446
455
50317
E325
L
N
R
R
P
S
T
E
S
E
T
D
T
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
92
98.5
N.A.
97.7
97.3
N.A.
77.6
91.5
86.9
81.2
N.A.
37.5
46.9
N.A.
56.2
Protein Similarity:
100
92.1
92
99.3
N.A.
98.7
98.3
N.A.
79.3
94.6
93.1
88.8
N.A.
55.5
60.9
N.A.
70.4
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
6.6
86.6
86.6
80
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
26.6
93.3
93.3
93.3
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
8
8
0
0
24
70
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% C
% Asp:
0
8
0
70
0
0
0
0
47
0
0
8
0
8
0
% D
% Glu:
0
0
8
0
8
0
54
16
24
8
0
0
0
16
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
0
8
8
0
0
0
0
16
16
0
0
62
62
% I
% Lys:
0
8
70
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
8
0
0
0
70
0
0
0
8
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
0
0
8
0
0
0
16
0
0
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
70
8
8
0
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
77
0
0
8
70
16
16
70
8
62
77
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
8
47
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _