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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NENF All Species: 20.3
Human Site: S153 Identified Species: 37.22
UniProt: Q9UMX5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMX5 NP_037481.1 172 18856 S153 R I L N E D G S P N L D F K P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108201 172 18711 S153 R I L N E D G S P N L D F K P
Dog Lupus familis XP_537145 151 16532 D136 E D G S P N L D F Q P E D Q P
Cat Felis silvestris
Mouse Mus musculus Q9CQ45 171 18886 S152 R I L N E D G S P N L D F K P
Rat Rattus norvegicus Q6IUR5 171 18973 S152 R I L N E D G S P N L D F K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509736 165 18361 S146 R I L N E D G S P N Q N F K P
Chicken Gallus gallus Q5ZKN2 192 21263 T176 L K D G E E P T V Y S D E E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CES0 267 29696 P160 F Y T E T G Q P T D A L L H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W376 287 32609 G170 G R F Y D E K G A L T T Y H H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XXA7 326 36224 P207 Y Y D S E G Q P T P E L T D V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002324923 100 10911 P93 K K F E A K Y P V V G R V V S
Maize Zea mays NP_001149328 232 24549 S177 V T V E D R S S A A S T A P G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SK39 100 11013 P93 T K F E A K Y P V V G R V V S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 70.3 N.A. 90.6 88.3 N.A. 77.3 28.6 N.A. 21.7 N.A. 25 N.A. 22.3 N.A.
Protein Similarity: 100 N.A. 98.8 75.5 N.A. 93.5 92.4 N.A. 84.8 44.7 N.A. 34.8 N.A. 36.5 N.A. 31.8 N.A.
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 86.6 13.3 N.A. 0 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. 100 33.3 N.A. 100 100 N.A. 93.3 33.3 N.A. 6.6 N.A. 20 N.A. 13.3 N.A.
Percent
Protein Identity: 29 30.6 N.A. 27.9 N.A. N.A.
Protein Similarity: 39.5 43.5 N.A. 41.8 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 20 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 0 0 0 16 8 8 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 16 0 16 39 0 8 0 8 0 39 8 8 0 % D
% Glu: 8 0 0 31 54 16 0 0 0 0 8 8 8 8 8 % E
% Phe: 8 0 24 0 0 0 0 0 8 0 0 0 39 0 0 % F
% Gly: 8 0 8 8 0 16 39 8 0 0 16 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 8 % H
% Ile: 0 39 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 24 0 0 0 16 8 0 0 0 0 0 0 39 0 % K
% Leu: 8 0 39 0 0 0 8 0 0 8 31 16 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 39 0 8 0 0 0 39 0 8 0 0 0 % N
% Pro: 0 0 0 0 8 0 8 31 39 8 8 0 0 8 47 % P
% Gln: 0 0 0 0 0 0 16 0 0 8 8 0 0 8 0 % Q
% Arg: 39 8 0 0 0 8 0 0 0 0 0 16 0 0 0 % R
% Ser: 0 0 0 16 0 0 8 47 0 0 16 0 0 0 16 % S
% Thr: 8 8 8 0 8 0 0 8 16 0 8 16 8 0 0 % T
% Val: 8 0 8 0 0 0 0 0 24 16 0 0 16 16 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 16 0 8 0 0 16 0 0 8 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _