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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NENF All Species: 19.39
Human Site: S77 Identified Species: 35.56
UniProt: Q9UMX5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMX5 NP_037481.1 172 18856 S77 G V V F D V T S G K E F Y G R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108201 172 18711 S77 G V V F D V T S G K E F Y G R
Dog Lupus familis XP_537145 151 16532 F60 D V T S G K E F Y G R G A P Y
Cat Felis silvestris
Mouse Mus musculus Q9CQ45 171 18886 S76 G V V F D V T S G K E F Y G R
Rat Rattus norvegicus Q6IUR5 171 18973 S76 G V V F D V T S G K E F Y G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509736 165 18361 S70 G V V F D V T S G K E F Y G R
Chicken Gallus gallus Q5ZKN2 192 21263 R100 G K V F D V T R A S K F Y G P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CES0 267 29696 K84 G Q V F D V E K G R K H Y G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W376 287 32609 R94 G S V F D V S R G I K H Y G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XXA7 326 36224 G131 G R V Y N V D G K K E Y Y G P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002324923 100 10911 S17 Q Y N G T N P S N P I Y V A L
Maize Zea mays NP_001149328 232 24549 Q101 G Q I Y D V T Q S R M F Y G P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SK39 100 11013 S17 Q Y N G T D E S K P I Y V A I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 70.3 N.A. 90.6 88.3 N.A. 77.3 28.6 N.A. 21.7 N.A. 25 N.A. 22.3 N.A.
Protein Similarity: 100 N.A. 98.8 75.5 N.A. 93.5 92.4 N.A. 84.8 44.7 N.A. 34.8 N.A. 36.5 N.A. 31.8 N.A.
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 100 60 N.A. 53.3 N.A. 53.3 N.A. 46.6 N.A.
P-Site Similarity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 100 66.6 N.A. 66.6 N.A. 66.6 N.A. 66.6 N.A.
Percent
Protein Identity: 29 30.6 N.A. 27.9 N.A. N.A.
Protein Similarity: 39.5 43.5 N.A. 41.8 N.A. N.A.
P-Site Identity: 6.6 46.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 66.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 8 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 70 8 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 24 0 0 0 47 0 0 0 0 % E
% Phe: 0 0 0 62 0 0 0 8 0 0 0 54 0 0 0 % F
% Gly: 77 0 0 16 8 0 0 8 54 8 0 8 0 77 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 8 16 0 0 0 8 % I
% Lys: 0 8 0 0 0 8 0 8 16 47 24 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 16 0 8 8 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 16 0 0 0 8 31 % P
% Gln: 16 16 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 16 0 16 8 0 0 0 39 % R
% Ser: 0 8 0 8 0 0 8 54 8 8 0 0 0 0 8 % S
% Thr: 0 0 8 0 16 0 54 0 0 0 0 0 0 0 0 % T
% Val: 0 47 70 0 0 77 0 0 0 0 0 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 16 0 0 0 0 8 0 0 24 77 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _