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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NENF All Species: 20.61
Human Site: Y133 Identified Species: 37.78
UniProt: Q9UMX5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMX5 NP_037481.1 172 18856 Y133 D E V F T K V Y K A K Y P I V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001108201 172 18711 Y133 D E V F T K V Y K A K Y P I V
Dog Lupus familis XP_537145 151 16532 Y116 N K V Y K A K Y P I V G Y T A
Cat Felis silvestris
Mouse Mus musculus Q9CQ45 171 18886 Y132 D D V F S K V Y K A K Y P I V
Rat Rattus norvegicus Q6IUR5 171 18973 Y132 D D I F S K V Y K A K Y P I V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509736 165 18361 Y126 D D I F T N V Y K A K Y P I V
Chicken Gallus gallus Q5ZKN2 192 21263 S156 E T L R D W E S Q F T F K Y H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CES0 267 29696 Q140 Y D W L S F Y Q R D Y T P V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W376 287 32609 F150 G L A G W R D F Y Q K D Y V Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XXA7 326 36224 D187 R D W V S F Y D K E Y P L V G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002324923 100 10911 L73 I S S S L H G L T E K E I G V
Maize Zea mays NP_001149328 232 24549 M157 Q D W E Y K F M S K Y V K V G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SK39 100 11013 L73 V S P S L E G L T E K E I N T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 70.3 N.A. 90.6 88.3 N.A. 77.3 28.6 N.A. 21.7 N.A. 25 N.A. 22.3 N.A.
Protein Similarity: 100 N.A. 98.8 75.5 N.A. 93.5 92.4 N.A. 84.8 44.7 N.A. 34.8 N.A. 36.5 N.A. 31.8 N.A.
P-Site Identity: 100 N.A. 100 13.3 N.A. 86.6 80 N.A. 80 0 N.A. 6.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 N.A. 100 33.3 N.A. 100 100 N.A. 93.3 26.6 N.A. 33.3 N.A. 26.6 N.A. 26.6 N.A.
Percent
Protein Identity: 29 30.6 N.A. 27.9 N.A. N.A.
Protein Similarity: 39.5 43.5 N.A. 41.8 N.A. N.A.
P-Site Identity: 13.3 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 20 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 0 0 0 39 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 39 47 0 0 8 0 8 8 0 8 0 8 0 0 0 % D
% Glu: 8 16 0 8 0 8 8 0 0 24 0 16 0 0 0 % E
% Phe: 0 0 0 39 0 16 8 8 0 8 0 8 0 0 0 % F
% Gly: 8 0 0 8 0 0 16 0 0 0 0 8 0 8 24 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 16 0 0 0 0 0 0 8 0 0 16 39 0 % I
% Lys: 0 8 0 0 8 39 8 0 47 8 62 0 16 0 0 % K
% Leu: 0 8 8 8 16 0 0 16 0 0 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 8 0 0 0 0 0 8 0 0 8 47 0 0 % P
% Gln: 8 0 0 0 0 0 0 8 8 8 0 0 0 0 0 % Q
% Arg: 8 0 0 8 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 16 8 16 31 0 0 8 8 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 24 0 0 0 16 0 8 8 0 8 8 % T
% Val: 8 0 31 8 0 0 39 0 0 0 8 8 0 31 47 % V
% Trp: 0 0 24 0 8 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 8 0 16 47 8 0 24 39 16 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _