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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUCA1B All Species: 16.39
Human Site: S197 Identified Species: 27.74
UniProt: Q9UMX6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMX6 NP_002089.4 200 23420 S197 L A Q Q R R K S A M F _ _ _ _
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086886 202 22999 A197 E E G A D K E A A E A A G _ _
Dog Lupus familis XP_538922 201 23483 S198 I S Q Q R R R S A M F _ _ _ _
Cat Felis silvestris
Mouse Mus musculus Q8VBV8 201 23501 S198 I T Q Q R R R S A M F _ _ _ _
Rat Rattus norvegicus P62749 193 22320 A190 L Q C D P S S A S Q F _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508360 199 23044
Chicken Gallus gallus P79881 198 23110 S195 I S E Q R R K S A L F _ _ _ _
Frog Xenopus laevis Q6DCM9 193 22267 T190 L Q C D P S S T S Q F _ _ _ _
Zebra Danio Brachydanio rerio Q6AXL4 192 21965
Tiger Blowfish Takifugu rubipres NP_001027857 197 22910
Fruit Fly Dros. melanogaster P42325 190 21875
Honey Bee Apis mellifera XP_392256 192 21952
Nematode Worm Caenorhab. elegans P36608 191 22003 G188 H A L S L Y E G L S S _ _ _ _
Sea Urchin Strong. purpuratus XP_783112 194 22350 S190 L Q C D P S G S A V T K _ _ _
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 45.5 88.5 N.A. 88 43 N.A. 78.5 77.5 43 43 76 42.5 44 35.5 42.5
Protein Similarity: 100 N.A. 63.3 96.5 N.A. 93.5 61 N.A. 88 89 61 60.5 86 60 62.5 56.5 61
P-Site Identity: 100 N.A. 7.6 72.7 N.A. 72.7 18.1 N.A. 0 63.6 18.1 0 0 0 0 9 25
P-Site Similarity: 100 N.A. 38.4 100 N.A. 90.9 36.3 N.A. 0 100 36.3 0 0 0 0 18.1 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 8 0 0 0 15 43 0 8 8 0 0 0 % A
% Cys: 0 0 22 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 22 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 8 8 0 0 0 15 0 0 8 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 8 8 0 0 0 0 8 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 8 15 0 0 0 0 8 0 0 0 % K
% Leu: 29 0 8 0 8 0 0 0 8 8 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 22 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 22 22 29 0 0 0 0 0 15 0 0 0 0 0 % Q
% Arg: 0 0 0 0 29 29 15 0 0 0 0 0 0 0 0 % R
% Ser: 0 15 0 8 0 22 15 36 15 8 8 0 0 0 0 % S
% Thr: 0 8 0 0 0 0 0 8 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 50 58 65 65 % _